| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Minireviews |
| Article Title |
Evolution of heart transplant donor characteristics in the 21st century: A United States single center’s experience
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Alexander M Spring, Christiana Gjelaj, Shivank Madan, Snehal R Patel, Omar Saeed, Sandhya Murthy, Yogita Rochlani, Daniel B Sims, Sasha Vukelic, Stephen J Forest, Jamil F Borgi, Daniel J Goldstein and Ulrich P Jorde |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ulrich P Jorde, MD, Doctor, Doctor, Professor, Montefiore-Einstein Center for Heart and Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, 111 East 210th Street, MMC-MAP Room 7, Bronx, NY 10467, United States. ujorde@montefiore.org |
| Key Words |
Orthotopic heart transplantation; Hepatitis C virus; COVID-19; Left ventricular systolic dysfunction; Human immunodeficiency virus; Donation after cardiac death |
| Core Tip |
Since the turn of the 21st century, advances in certain laboratory studies, pharmacologic interventions, and organ care systems have led to the expansion of the donor pool in the field of orthotopic heart transplantation. This includes: (1) Nucleic acid testing and direct acting antivirals for donors with hepatitis C virus; (2) Organ care systems for donors who meet criteria for donation after cardiac death; (3) Anti-viral therapies for donors with coronavirus disease 19; (4) Improved donor management for grafts with left ventricular systolic dysfunction; and (5) Better understanding of immunosuppression and medication interaction in patients with human immunodeficiency virus. We detail how these advances have allowed our center to expand the donor pool thereby increasing transplantation volume without adverse effects on outcomes. |
| Publish Date |
2024-07-31 07:20 |
| Citation |
<p>Spring AM, Gjelaj C, Madan S, Patel SR, Saeed O, Murthy S, Rochlani Y, Sims DB, Vukelic S, Forest SJ, Borgi JF, Goldstein DJ, Jorde UP. Evolution of heart transplant donor characteristics in the 21st century: A United States single center’s experience. <i>World J Transplant</i> 2024; 14(3): 92721</p> |
| URL |
https://www.wjgnet.com/2220-3230/full/v14/i3/92721.htm |
| DOI |
https://dx.doi.org/10.5500/wjt.v14.i3.92721 |
