Publication Name	World Journal of Clinical Cases
Manuscript ID	92781
Country	China

Received	2024-02-16 14:17
Peer-Review Started	2024-02-16 14:17
To Make the First Decision
Return for Revision	2024-03-05 20:02
Revised	2024-03-15 18:07
Second Decision	2024-04-09 03:14
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-04-09 08:01
Articles in Press	2024-04-09 08:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-05-08 06:57
Publish the Manuscript Online	2024-05-14 08:48

ISSN	2307-8960 (online)
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Category	Oncology
Manuscript Type	Case Report
Article Title	Cetuximab combined with chemotherapy for simultaneous esophageal squamous cell carcinoma and colon adenocarcinoma: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Xin-Xin Luo, Yu-Xuan Du, Qi-Qing Zhang, Lin Zhang, Shu-Ying Zeng, Zhi-Hong Yu, Peng Shen and Zheng-Quan Feng
ORCID	Author(s) ORCID Number Xin-Xin Luo http://orcid.org/0009-0000-2479-3779 Yu-Xuan Du http://orcid.org/0009-0000-5043-7049 Qi-Qing Zhang http://orcid.org/0009-0009-2666-0182 Lin Zhang http://orcid.org/0009-0003-1964-2142 Shu-Ying Zeng http://orcid.org/0009-0009-7495-4994 Zhi-Hong Yu http://orcid.org/0000-0001-8304-1833 Peng Shen http://orcid.org/0000-0002-1123-9848 Zheng-Quan Feng http://orcid.org/0009-0001-9060-8671
Funding Agency and Grant Number
Corresponding Author	Zheng-Quan Feng, MD, PhD, Chief Physician, Director, Director, Department of Oncology, Tongde Hospital of Zhejiang Province, No. 234 Gucui Road, Xihu District, Hangzhou 310012, Zhejiang Province, China. fzhq213@aliyun.com
Key Words	Synchronous multiple primary carcinoma; Esophageal squamous cell carcinoma; Colon adenocarcinoma; Cetuximab; Chemotherapy; Case report
Core Tip	We report a case of a 64-year-old patient diagnosed with synchronous esophageal squamous cell carcinoma and colon adenocarcinoma with liver metastasis. After multi-disciplinary consultations, oxaliplatin + capecitabine chemotherapy and esophageal cancer radiotherapy were initiated. Based on genetic testing, treatment was switched to a regimen of leucovorin + fluorouracil + oxaliplatin and cetuximab for 8 cycles. Subsequently, capecitabine and bevacizumab were administered, and the tumor was stable at the most recent follow-up. This case demonstrates successful treatment of dual primary digestive tract tumors of differing pathological types using the same regimen, which supports non-surgical, simultaneous treatment for synchronous multiple primary cancers.
Publish Date	2024-05-14 08:48
Citation	<p>Luo XX, Du YX, Zhang QQ, Zhang L, Zeng SY, Yu ZH, Shen P, Feng ZQ. Cetuximab combined with chemotherapy for simultaneous esophageal squamous cell carcinoma and colon adenocarcinoma: A case report. <i>World J Clin Cases</i> 2024; 12(15): 2649-2654</p>
URL	https://www.wjgnet.com/2307-8960/full/v12/i15/2649.htm
DOI	https://dx.doi.org/10.12998/wjcc.v12.i15.2649

Full Article (PDF)	WJCC-12-2649-with-cover.pdf
CARE Checklist–2016	92781-CARE Checklist (2016).pdf
Manuscript File	92781_Auto_Edited-YJP.docx
Answering Reviewers	92781-Answering reviewers.pdf
Audio Core Tip	92781-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	92781-Conflict-of-interest statement.pdf
Copyright License Agreement	92781-Copyright license agreement.pdf
Signed Consent for Treatment Form(s) or Document(s)	92781-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	92781-Language certificate.pdf
Peer-review Report	92781-Peer-review(s).pdf
Scientific Misconduct Check	92781-Bing-Zheng XM-2.png
Scientific Misconduct Check	92781-CrossCheck.png
Scientific Editor Work List	92781-Scientific editor work list.pdf
CrossCheck Report	92781-CrossCheck report.pdf