Publication Name	World Journal of Hepatology
Manuscript ID	92877
Country	China

Received	2024-02-08 14:48
Peer-Review Started	2024-02-08 14:48
To Make the First Decision
Return for Revision	2024-04-17 01:09
Revised	2024-04-28 17:07
Second Decision	2024-05-17 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-05-17 07:32
Articles in Press	2024-05-17 07:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-05-31 09:04
Publish the Manuscript Online	2024-06-20 03:42

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Liver histological changes in untreated chronic hepatitis B patients in indeterminate phase
Manuscript Source	Unsolicited Manuscript
All Author List	De-Liang Huang, Qin-Xian Cai, Guang-De Zhou, Hong Yu, Zhi-Bin Zhu, Jing-Han Peng and Jun Chen
ORCID	Author(s) ORCID Number De-Liang Huang http://orcid.org/0000-0002-6154-017X Hong Yu http://orcid.org/0000-0003-0199-1494 Zhi-Bin Zhu http://orcid.org/0000-0002-8738-6211 Jing-Han Peng http://orcid.org/0000-0002-4869-0085 Jun Chen http://orcid.org/0000-0002-9744-792X
Funding Agency and Grant Number	Funding Agency Grant Number Construction of Key Medical Disciplines in Shenzhen No.SZXK076
Corresponding Author	Jun Chen, PhD, Professor, Department of Liver Diseases, The Third People’s Hospital of Shenzhen, No. 29 Shenzhen Long Gang Bulan Road, Shenzhen 510000, Guangdong Province, China. drchenjun@163.com
Key Words	Chronic hepatitis B; Indeterminate phase; Gray-zone; Liver biopsy; Pathological histology; Risk factors
Core Tip	In this study, we investigated liver histological changes in 814 chronic hepatitis B patients in the indeterminate phase, in which significant liver histological changes (defined as biopsy score ≥ G2 and/or ≥ S2) were found in 488/814 (59.95%) patients, which suggested that additional strategies are urgently required for management of these patients.
Publish Date	2024-06-20 03:42
Citation	<p>Huang DL, Cai QX, Zhou GD, Yu H, Zhu ZB, Peng JH, Chen J. Liver histological changes in untreated chronic hepatitis B patients in indeterminate phase. <i>World J Hepatol</i> 2024; 16(6): 920-931</p>
URL	https://www.wjgnet.com/1948-5182/full/v16/i6/920.htm
DOI	https://dx.doi.org/10.4254/wjh.v16.i6.920

Full Article (PDF)	WJH-16-920-with-cover.pdf
STROBE Statement	92877-STROBE-statement.pdf
Manuscript File	92877_Auto_Edited-YJP.docx
Answering Reviewers	92877-answering-reviewers.pdf
Audio Core Tip	92877-audio.m4a
Biostatistics Review Certificate	92877-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	92877-conflict-of-interest-statement.pdf
Copyright License Agreement	92877-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	92877-foundation-statement.pdf
Signed Informed Consent Form(s) or Document(s)	92877-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	92877-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	92877-non-native-speakers.pdf
Supplementary Material	92877-supplementary-material.pdf
Peer-review Report	92877-peer-reviews.pdf
Scientific Misconduct Check	92877-scientific-misconduct-check.jpg
Scientific Editor Work List	92877-scientific-editor-work-list.pdf
CrossCheck Report	92877-crosscheck-report.pdf