Publication Name	World Journal of Orthopedics
Manuscript ID	92898
Country	United States

Received	2024-02-09 17:32
Peer-Review Started	2024-02-09 17:32
To Make the First Decision
Return for Revision	2024-06-04 04:52
Revised	2024-07-19 21:00
Second Decision	2024-07-29 02:49
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-07-29 07:35
Articles in Press	2024-07-29 07:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-08-02 07:52
Publish the Manuscript Online	2024-08-13 09:40

ISSN	2218-5836 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: Https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Orthopedics
Manuscript Type	Prospective Study
Article Title	Blood metal concentrations and cardiac structure and function in total joint arthroplasty patients
Manuscript Source	Unsolicited Manuscript
All Author List	Peter C Brennan, Stephanie M Peterson, Thomas J O'Byrne, Mariana L Laporta, Cody C Wyles, Paul J Jannetto, Garvan C Kane, Maria Vassilaki and Hilal Maradit Kremers
ORCID	Author(s) ORCID Number Hilal Maradit Kremers http://orcid.org/0000-0003-3882-602X
Funding Agency and Grant Number	Funding Agency Grant Number The National Institutes of Health No. R01HL147155 The National Institutes of Health No. R01AG060920
Corresponding Author	Hilal Maradit Kremers, MD, Professor, Department of Quantitative Health Sciences, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, United States. maradit@mayo.edu
Key Words	Total joint arthroplasty; Metal-on-metal; Cardiotoxicity; Heart failure; Echocardiography; Cobalt
Core Tip	This study evaluated echocardiographic measures in 110 prospectively recruited total joint arthroplasty patients who had a recent history of elevated metal concentrations. Elevated cobalt and titanium concentrations were positively associated with some structural and functional cardiac changes.
Publish Date	2024-08-13 09:40
Citation	<p>Brennan PC, Peterson SM, O'Byrne TJ, Laporta ML, Wyles CC, Jannetto PJ, Kane GC, Vassilaki M, Maradit Kremers H. Blood metal concentrations and cardiac structure and function in total joint arthroplasty patients. <i>World J Orthop</i> 2024; 15(8): 773-782</p>
URL	https://www.wjgnet.com/2218-5836/full/v15/i8/773.htm
DOI	https://dx.doi.org/10.5312/wjo.v15.i8.773

Full Article (PDF)	WJO-15-773-with-cover.pdf
CONSORT 2010 Statement	92898-CONSORT-2010-statement.pdf
Manuscript File	92898_Auto_Edited_073934.docx
Answering Reviewers	92898-answering-reviewers.pdf
Audio Core Tip	92898-audio.m4a
Biostatistics Review Certificate	92898-biostatistics-statement.pdf
Clinical Trial Registration Statement	92898-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form	92898-conflict-of-interest-statement.pdf
Copyright License Agreement	92898-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	92898-foundation-statement.pdf
Signed Informed Consent Form(s) or Document(s)	92898-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	92898-institutional-review-board-statement.pdf
Peer-review Report	92898-peer-reviews.pdf
Scientific Misconduct Check	92898-scientific-misconduct-check.png
Scientific Editor Work List	92898-scientific-editor-work-list.pdf
CrossCheck Report	92898-crosscheck-report.pdf