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11/17/2014 3:13:00 PM | Browse: 1124 | Download: 1246
Publication Name World Journal of Gastroenterology
Manuscript ID 9316
Country/Territory China
Received
2014-01-30 10:41
Peer-Review Started
2014-02-08 09:40
To Make the First Decision
2014-02-28 14:53
Return for Revision
2014-03-13 09:28
Revised
2014-04-22 22:43
Second Decision
2014-05-14 09:25
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-05-14 09:29
Articles in Press
2014-05-23 10:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-05-21 16:19
Typeset the Manuscript
2014-10-30 15:14
Publish the Manuscript Online
2014-11-17 15:12
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Autobiography
Article Title Esophageal Helicobacter pylori colonization aggravates esophageal injury caused by reflux
Manuscript Source Unsolicited Manuscript
All Author List Yun-Xiang Chu, Wei-Hong Wang, Yun Dai, Gui-Gen Teng and Shu-Jun Wang
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81172271
Specialized Research Fund for the Doctoral Program of Higher Education 20110001110064
Corresponding Author Wei-Hong Wang, Professor, Department of Gastroenterology, Peking University First Hospital, 8 Xishiku Avenue, Xicheng District, Beijing 100034, China. wangweihong@medmail.com.cn
Key Words Helicobacter pylori; Esophagus; Metaplasia; Adenocarcinoma; Animal model
Core Tip The relationship between gastroesophageal reflux disease and Helicobacter pylori (H. pylori) is controversial. This study demonstrates that esophageal H. pylori colonization can aggravate esophageal injury and promote the incidence of Barrett’s esophagus and esophageal adenocarcinoma. Gastric H. pylori colonization did not aggravate esophageal mucosal lesions in rats with mixed reflux. However, esophageal H. pylori infection was associated with increased cell proliferation and apoptosis in the esophagi of rats with mixed reflux. Loss of balance between cell proliferation and apoptosis may be important in H. pylori-induced esophageal malignancy.
Publish Date 2014-11-17 15:12
Citation Chu YX, Wang WH, Dai Y, Teng GG, Wang SJ. Esophageal Helicobacter pylori colonization aggravates esophageal injury caused by reflux. World J Gastroenterol 2014; 20(42): 15715-15726
URL http://www.wjgnet.com/1007-9327/full/v20/i42/15715.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i42.15715
Full Article (PDF) WJG-20-15715.pdf
Full Article (Word) WJG-20-15715.doc
Manuscript File 9316-Review.doc
Answering Reviewers 9316-Answering reviewers.pdf
Copyright License Agreement 9316-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 9316-Language certificate.pdf
Peer-review Report 9316-Peer reviews.pdf
Scientific Editor Work List 9316-Scientific editor work list.pdf