Publication Name	World Journal of Stem Cells
Manuscript ID	93183
Country	Italy

Received	2024-02-21 11:29
Peer-Review Started	2024-02-21 11:29
To Make the First Decision
Return for Revision	2024-03-31 03:45
Revised	2024-04-09 11:05
Second Decision	2024-04-25 02:55
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-04-25 07:53
Articles in Press	2024-04-25 07:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-05-13 09:18
Publish the Manuscript Online	2024-05-24 08:33

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Biochemistry & Molecular Biology
Manuscript Type	Editorial
Article Title	Deer antler stem cell niche: An interesting perspective
Manuscript Source	Invited Manuscript
All Author List	Claudia Cavallini, Elena Olivi, Riccardo Tassinari, Chiara Zannini, Gregorio Ragazzini, Martina Marcuzzi, Valentina Taglioli and Carlo Ventura
ORCID	Author(s) ORCID Number Claudia Cavallini http://orcid.org/0000-0002-8079-9697 Elena Olivi http://orcid.org/0000-0002-8999-1538 Riccardo Tassinari http://orcid.org/0000-0002-9425-1841 Chiara Zannini http://orcid.org/0000-0003-3925-4844 Gregorio Ragazzini http://orcid.org/0000-0002-6876-5080 Martina Marcuzzi http://orcid.org/0000-0002-8965-3168 Valentina Taglioli http://orcid.org/0000-0002-0687-9576 Carlo Ventura http://orcid.org/0000-0001-9333-0321
Funding Agency and Grant Number
Corresponding Author	Carlo Ventura, MD, PhD, Director, Director, Full Professor, National Laboratory of Molecular Biology and Stem Cell Engineering, National Institute of Biostructures and Biosystems - Eldor Lab, Via Corticella 183, Bologna 40128, Italy. carlo.ventura@unibo.it
Key Words	Extracellular matrix; Antler stem cells; Stem cell niche; Regenerative medicine or tissue regeneration; Decellularized scaffolds; Cell memory
Core Tip	Recent research has focused on enhancing cell regenerative capacity through biomaterials, particularly natural scaffolds. A novel study published in World J Stem Cells investigates the possibility of using a decellularized xenogeneic extracellular matrix (ECM) from antler stem cells to repair osteochondral defects in rats. Our editorial emphasizes the vital role of biological scaffolds in boosting stem cell potential and regenerative abilities by creating a favorable microenvironment. Stem cell differentiation relies on the ECM properties, including its chemical composition and mechanical forces. This bio-instructive signaling environment offers tissue-specific guidance for effective repair and regeneration, aligning with the growing interest in mechanobiology.
Publish Date	2024-05-24 08:33
Citation	<p>Cavallini C, Olivi E, Tassinari R, Zannini C, Ragazzini G, Marcuzzi M, Taglioli V, Ventura C. Deer antler stem cell niche: An interesting perspective. <i>World J Stem Cells</i> 2024; 16(5): 479-485</p>
URL	https://www.wjgnet.com/1948-0210/full/v16/i5/479.htm
DOI	https://dx.doi.org/10.4252/wjsc.v16.i5.479

Full Article (PDF)	WJSC-16-479-with-cover.pdf
Full Article (Word)	WJSC-16-479.docx
Manuscript File	93183_Auto_Edited-YJP.docx
Answering Reviewers	93183-Answering reviewers.pdf
Audio Core Tip	93183-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	93183-Conflict-of-interest statement.pdf
Copyright License Agreement	93183-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	93183-Language certificate.pdf
Peer-review Report	93183-Peer-review(s).pdf
Scientific Misconduct Check	93183-Bing-Wang JJ-2.png
Scientific Editor Work List	93183-Scientific editor work list.pdf
CrossCheck Report	93183-CrossCheck report.pdf