BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
7/12/2024 3:55:58 PM | Browse: 164 | Download: 825
 |
Received |
|
2024-02-23 09:59 |
|
Peer-Review Started |
|
2024-02-23 09:59 |
|
First Decision by Editorial Office Director |
|
2024-04-13 05:30 |
|
Return for Revision |
|
2024-04-13 05:30 |
|
Revised |
|
2024-04-29 07:38 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2024-05-17 02:44 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2024-05-17 06:24 |
|
Articles in Press |
|
2024-05-17 06:24 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2024-06-24 00:12 |
|
Publish the Manuscript Online |
|
2024-07-12 15:55 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Aldehyde dehydrogenase 2 family member repression promotes colorectal cancer progression by JNK/p38 MAPK pathways-mediated apoptosis and DNA damage
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Miao Yu, Qian Chen and Yi-Ping Lu |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Beijing Municipal Hospital Research and Cultivation Program Project |
PZ2022008 |
|
| Corresponding Author |
Yi-Ping Lu, MM, Chief Physician, Department of Surgical Oncology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, No. 23 Art Museum Back Street, Beijing 100010, China. 15210712026@163.com |
| Key Words |
Aldehyde dehydrogenase 2 family member; Colorectal cancer; Acetaldehyde; Apoptosis; DNA damage; JNK/p38 MAPK |
| Core Tip |
This work demonstrated that aldehyde dehydrogenase 2 family member (ALDH2) repression caused the accumulation of acetaldehyde, inducing cell apoptosis and DNA damage by means of activating the JNK/p38 MAPK signaling pathway in colorectal cancer (CRC). ALDH2 is utilized as a therapeutic target for reversing patients with CRC. |
| Publish Date |
2024-07-12 15:55 |
| Citation |
Yu M, Chen Q, Lu YP. Aldehyde dehydrogenase 2 family member repression promotes colorectal cancer progression by JNK/p38 MAPK pathways-mediated apoptosis and DNA damage. World J Gastrointest Oncol 2024; 16(7): 3230-3240 |
| URL |
https://www.wjgnet.com/1948-5204/full/v16/i7/3230.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v16.i7.3230 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
