ISSN |
2219-2808 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Systematic Reviews |
Article Title |
Fecal calprotectin in pediatric gastrointestinal diseases: Pros and cons
|
Manuscript Source |
Invited Manuscript |
All Author List |
Mohammed Al-Beltagi, Nermin Kamal Saeed, Adel Salah Bediwy and Reem Elbeltagi |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Mohammed Al-Beltagi, MBChB, MD, PhD, Academic Editor, Chairman, Professor, Research Scientist, Department of Pediatric , Faculty of Medicine, Tanta University, Al-Bahr street, The Medical Complex, Tanta 31511, Alghrabia, Egypt. mbelrem@hotmail.com |
Key Words |
Fecal calprotectin; Pediatric gastrointestinal diseases; Functional gastrointestinal disorders; Inflammatory bowel disease; Coeliac disease; COVID-19-induced gastrointestinal disorders; Infectious gastroenteritis; Cystic fibrosis |
Core Tip |
The core findings of this systematic review underscore the pivotal role of fecal calprotectin as a non-invasive marker for assessing intestinal inflammation in pediatric gastrointestinal diseases. Through an extensive systematic literature review, it was evident that fecal calprotectin provides valuable insights into disease activity, treatment response, and prognosis across various conditions, including functional gastrointestinal disorders, inflammatory bowel disease, coeliac disease, coronavirus disease 2019 induced gastrointestinal disorders, gastroenteritis, and cystic fibrosis-associated intestinal pathology. Despite its limitations in specificity and susceptibility to confounding factors, fecal calprotectin remains a valuable tool in pediatric gastroenterology, offering clinicians a means to diagnose, monitor, and manage gastrointestinal diseases effectively. |
Publish Date |
2024-06-07 13:38 |
Citation |
<p>Al-Beltagi M, Saeed NK, Bediwy AS, Elbeltagi R. Fecal calprotectin in pediatric gastrointestinal diseases: Pros and cons. <i>World J Clin Pediatr</i> 2024; 13(2): 93341</p> |
URL |
https://www.wjgnet.com/2219-2808/full/v13/i2/93341.htm |
DOI |
https://dx.doi.org/10.5409/wjcp.v13.i2.93341 |