Publication Name	World Journal of Clinical Oncology
Manuscript ID	93388
Country	China

Received	2024-02-26 10:53
Peer-Review Started	2024-02-26 10:53
To Make the First Decision
Return for Revision	2024-04-29 20:51
Revised	2024-05-11 09:18
Second Decision	2024-06-06 02:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-06-06 08:56
Articles in Press	2024-06-06 08:56
Publication Fee Transferred	2024-06-10 04:03
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-07-08 01:28
Publish the Manuscript Online	2024-07-16 06:17

ISSN	2218-4333 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: Https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Cell Biology
Manuscript Type	Basic Study
Article Title	Parthenolide enhances the metronomic chemotherapy effect of cyclophosphamide in lung cancer by inhibiting the NF-kB signaling pathway
Manuscript Source	Unsolicited Manuscript
All Author List	Zheng Cai, Lang Gao, Kai Hu and Qi-Ming Wang
ORCID	Author(s) ORCID Number Zheng Cai http://orcid.org/0000-0001-7996-2322 Qi-Ming Wang http://orcid.org/0000-0003-3217-1077
Funding Agency and Grant Number	Funding Agency Grant Number Joint Funding of Yunnan Ministry of Science and Technology 2019FF002-048 Beijing Heathco Clinical Oncology Research Foundation Y-Q201802-048
Corresponding Author	Qi-Ming Wang, PhD, Doctor, Doctor, Department of Internal Medicine, The Affiliated Cancer Hospital of Zhengzhou University, No. 127 Dong Ming Road, Zhengzhou 450008, Henan Province, China. qimingwang1006@126.com
Key Words	Lung cancer; Parthenolide; Cyclophosphamide; Rhythmic chemotherapy; NF-κB pathway
Core Tip	Our present study found that as a specific inhibitor of NF-kB, Parthenolide can promote the efficiency of cyclophosphamide in lung cancer via inhibiting NF-kB signaling in vitro and in vivo. Our present study will help scientists and clinicians to draw up novel rhythmic chemotherapy strategies.
Publish Date	2024-07-16 06:17
Citation	<p>Cai Z, Gao L, Hu K, Wang QM. Parthenolide enhances the metronomic chemotherapy effect of cyclophosphamide in lung cancer by inhibiting the NF-kB signaling pathway. <i>World J Clin Oncol</i> 2024; 15(7): 895-907</p>
URL	https://www.wjgnet.com/2218-4333/full/v15/i7/895.htm
DOI	https://dx.doi.org/10.5306/wjco.v15.i7.895

Full Article (PDF)	WJCO-15-895-with-cover.pdf
The ARRIVE Guidelines	93388-The-ARRIVE-Guidelines.pdf
Manuscript File	93388_Auto_Edited-YJP.docx
Answering Reviewers	93388-answering-reviewers.pdf
Audio Core Tip	93388-audio.mp3
Biostatistics Review Certificate	93388-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	93388-conflict-of-interest-statement.pdf
Copyright License Agreement	93388-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	93388-foundation-statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document	93388-institutional-animal-care-and-use-committee-statement.pdf
Non-Native Speakers of English Editing Certificate	93388-non-native-speakers.pdf
Supplementary Material	93388-supplementary-material.pdf
Peer-review Report	93388-peer-reviews.pdf
Scientific Misconduct Check	93388-scientific-misconduct-check.png
Scientific Editor Work List	93388-scientific-editor-work-list.pdf
CrossCheck Report	93388-crosscheck-report.png
CrossCheck Report	93388-crosscheck-report.pdf