| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Hematology |
| Manuscript Type |
Case Report |
| Article Title |
Luspatercept enhances hemoglobin levels in a Chinese boy with congenital sideroblastic anemia: A case report
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yuan Li, Lei Ye, Kang Zhou, Hui-Hui Fan, Jian-Ping Li, You-Zhen Xiong, Yang Yang, Guang-Xin Peng, Wen-Rui Yang, Xin Zhao, Li-Ping Jing, Li Zhang and Feng-Kui Zhang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81890992 |
|
| Corresponding Author |
Feng-Kui Zhang, PhD, Professor, Anemia Therapeutic Center, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Science, Peking Union Medical College, No. 288 Nanjing Road, Heping District, Tianjin 300020, China. fkzhang@ihcams.ac.cn |
| Key Words |
Anemia; Sideroblastic anemia; Luspatercept; Congenital; Lifespan of mature red blood cells; Microcytic anemia; Case report |
| Core Tip |
Congenital sideroblastic anemia (CSA) is a rare and heterogeneous group of genetic disorders. Conventional treatment include pyridoxine (vitamin B6) and allogeneic hematopoietic stem cell transplantation (allo-HSCT), and can alleviate anemia in the majority of cases. Nevertheless, some CSA cases remain unresponsive to pyridoxine or are unable to undergo allo-HSCT. Novel management approaches is necessary to be developed. We present a case of luspatercept administered to enhance hemoglobin Levels. |
| Publish Date |
2024-06-29 10:30 |
| Citation |
<p>Li Y, Ye L, Zhou K, Fan HH, Li JP, Xiong YZ, Yang Y, Peng GX, Yang WR, Zhao X, Jing LP, Zhang L, Zhang FK. Luspatercept enhances hemoglobin levels in a Chinese boy with congenital sideroblastic anemia: A case report. <i>World J Clin Cases</i> 2024; 12(19): 3978-3984</p> |
| URL |
https://www.wjgnet.com/2307-8960/full/v12/i19/3978.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v12.i19.3978 |
