ISSN |
1948-5182 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Prospective Study |
Article Title |
Predictors of survival in autoimmune liver disease overlap syndromes
|
Manuscript Source |
Unsolicited Manuscript |
All Author List |
Dujinthan Jayabalan, Yi Huang, Luis Calzadilla-Bertot, Malik Janjua, Bastiaan de Boer, John Joseph, Wendy Cheng, Simon Hazeldine, Briohny W Smith, Gerry C MacQuillan, Michael C Wallace, George Garas, Leon A Adams and Gary P Jeffrey |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Dujinthan Jayabalan, BSc, MD, Doctor, Doctor, Lecturer, Medical School, University of Western Australia, 35 Stirling Highway, Nedlands 6009, Western Australia, Australia. duji.jayabalan@uwa.edu.au |
Key Words |
Autoimmune liver disease overlap syndromes; Liver outcome score; Liver-related death; Hepascore; Autoimmune hepatitis; Primary biliary cholangitis; Primary sclerosing cholangitis |
Core Tip |
The rare, autoimmune liver disease overlap syndromes (AILDOS), currently have no predictors of survival. AILDOS can be further classified into Autoimmune Hepatitis and Primary Biliary Cholangitis Overlap (AIH-PBC) and Autoimmune Hepatitis and Primary Sclerosing Cholangitis Overlap. Liver-related mortality was defined as liver-related death or liver transplantation. This study validates the liver outcome score as a predictive model of liver-mortality in AIH-PBC patients. The model for end-stage liver disease (MELD) score, Na-MELD score and Mayo score were not predictive of liver-related mortality in any group. |
Publish Date |
2024-09-23 10:30 |
Citation |
<p>Jayabalan D, Huang Y, Calzadilla-Bertot L, Janjua M, de Boer B, Joseph J, Cheng W, Hazeldine S, Smith BW, MacQuillan GC, Wallace MC, Garas G, Adams LA, Jeffrey GP. Predictors of survival in autoimmune liver disease overlap syndromes. <i>World J Hepatol</i> 2024; 16(9): 1269-1277</p> |
URL |
https://www.wjgnet.com/1948-5182/full/v16/i9/1269.htm |
DOI |
https://dx.doi.org/10.4254/wjh.v16.i9.1269 |