Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	93586
Country	China

Received	2024-03-14 14:16
Peer-Review Started	2024-03-14 14:16
To Make the First Decision
Return for Revision	2024-04-25 12:38
Revised	2024-05-09 07:05
Second Decision	2024-06-04 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-06-04 06:30
Articles in Press	2024-06-04 06:30
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-06-25 14:45
Typeset the Manuscript	2024-06-30 14:52
Publish the Manuscript Online	2024-07-22 11:57

ISSN	1948-9366 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Yangyin Huowei mixture alleviates chronic atrophic gastritis by inhibiting the IL-10/JAK1/STAT3 pathway
Manuscript Source	Unsolicited Manuscript
All Author List	Shan-Shan Xie, Yong Zhi, Chang-Ming Shao and Bin-Fang Zeng
ORCID	Author(s) ORCID Number Bin-Fang Zeng http://orcid.org/0009-0002-0026-6266
Funding Agency and Grant Number	Funding Agency Grant Number the Project of Regional Collaborative Innovation of Xinjiang Uygur Autonomous Region 2022E01008 the Graduate Innovation Project of Xinjiang Medical University CXCY2023012
Corresponding Author	Bin-Fang Zeng, PhD, Professor, Traditional Chinese Medicine, Xinjiang Medical University, No. 567, Shangde North Road, Shuimogou District, Urumqi 830017, Xinjiang Uygur Autonomous Region, China. xjmuzbf@126.com
Key Words	Yangyin Huowei mixture; IL-10/JAK1/STAT3 pathway; Chronic atrophic gastritis; Inflammatory factor; Gastric secretory function
Core Tip	This study aimed to investigate the therapeutic effects of Yangyin Huowei mixture (YYHWM)on chronic atrophic gastritis (CAG) and its potential mechanism. The CAG model was induced through the administration of a composite factor. The study observed the pathological damage to the stomach tissue, gastric secretory function, inflammatory factors, and protein expression levels of the IL-10/JAK1/STAT3 pathway. Ultimately, it was discovered that YYHWM can improve the pathological damage to the stomach tissue and enhance the gastric secretory function of CAG rats, which may be attributed to its suppression of the IL-10/JAK1/STAT3 pathway and reduction of inflammatory factor levels.
Publish Date	2024-07-22 11:57
Citation	<p>Xie SS, Zhi Y, Shao CM, Zeng BF. Yangyin Huowei mixture alleviates chronic atrophic gastritis by inhibiting the IL-10/JAK1/STAT3 pathway. <i>World J Gastrointest Surg</i> 2024; 16(7): 2296-2307</p>
URL	https://www.wjgnet.com/1948-9366/full/v16/i7/2296.htm
DOI	https://dx.doi.org/10.4240/wjgs.v16.i7.2296

Full Article (PDF)	WJGS-16-2296-with-cover.pdf
Full Article (Word)	WJGS-16-2296.docx
The ARRIVE Guidelines	93586-The-ARRIVE-Guidelines.pdf
Manuscript File	93586_Auto_Edited-YJP_WangTQ.docx
Answering Reviewers	93586-answering-reviewers.pdf
Audio Core Tip	93586-audio.m4a
Biostatistics Review Certificate	93586-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	93586-conflict-of-interest-statement.pdf
Copyright License Agreement	93586-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	93586-foundation-statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document	93586-institutional-animal-care-and-use-committee-statement.pdf
Institutional Review Board Approval Form or Document	93586-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	93586-non-native-speakers.pdf
Peer-review Report	93586-peer-reviews.pdf
Scientific Misconduct Check	93586-scientific-misconduct-check.png
Scientific Editor Work List	93586-scientific-editor-work-list.pdf
CrossCheck Report	93586-crosscheck-report.png
CrossCheck Report	93586-crosscheck-report.pdf