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2/28/2025 10:47:06 AM | Browse: 127 | Download: 633
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Received |
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2024-03-02 12:46 |
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Peer-Review Started |
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2024-03-02 12:46 |
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First Decision by Editorial Office Director |
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2024-08-24 18:17 |
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Return for Revision |
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2024-08-24 18:17 |
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Revised |
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2024-09-16 14:16 |
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Publication Fee Transferred |
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2025-01-23 10:13 |
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Second Decision by Editor |
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2024-10-23 01:38 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-01-20 09:15 |
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Articles in Press |
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2025-01-20 09:15 |
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Edit the Manuscript by Language Editor |
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2025-01-30 00:45 |
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Typeset the Manuscript |
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2025-02-21 03:00 |
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Publish the Manuscript Online |
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2025-02-28 10:47 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Urology & Nephrology |
| Manuscript Type |
Basic Study |
| Article Title |
miR-29a-3p inhibit fibrosis of diabetic kidney disease in db/db mice via down-expression of DNMT3A/3B
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ying Yang, Yi Chen, Jian-Ying Tang, Jian Chen, Gui-Qing Li, Bing Feng and Jiao Mu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Chongqing Basic Research and Frontier Exploration Project |
No. cstc2018jcyjAX0834 |
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| Corresponding Author |
Jiao Mu, Department of Nephrology, Chongqing Medical University, No. 55 University City Road, Chongqing 401331, China. 800273@cqmu.edu.cn |
| Key Words |
Diabetic kidney disease; Mir-29a-3p; DNA methylation; Janus kinase/signal transducer and activator of transcription; Wnt/ β-catenin; Renal fibrosis |
| Core Tip |
This study was first verified that MiR-29a-3p can regulate Wnt/β-catenin and JAK/STAT signal pathways by regulating and inhibiting the expression of DNMT3A/3B, and thus participate in the inhibition of Diabetic Kidney Disease（DKD）-related fibrosis by in vitro and in vivo experiments. These findings indicate that targeting miR-29a-3p and DNMT3A/3B may hold promise for DKD prevention and treatment. |
| Publish Date |
2025-02-28 10:47 |
| Citation |
Yang Y, Chen Y, Tang JY, Chen J, Li GQ, Feng B, Mu J. miR-29a-3p inhibit fibrosis of diabetic kidney disease in db/db mice via down-expression of DNMT3A/3B. World J Diabetes 2025; 16(4): 93630 |
| URL |
https://www.wjgnet.com/1948-9358/full/v16/i4/93630.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v16.i4.93630 |
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