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11/7/2024 5:10:59 AM | Browse: 41 | Download: 100
Publication Name World Journal of Clinical Cases
Manuscript ID 93632
Country India
Received
2024-03-02 14:25
Peer-Review Started
2024-03-02 14:25
To Make the First Decision
Return for Revision
2024-09-15 18:59
Revised
2024-09-22 15:33
Second Decision
2024-10-23 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2024-10-23 11:29
Articles in Press
2024-10-23 11:29
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2024-10-25 00:27
Publish the Manuscript Online
2024-11-07 05:10
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Letter to the Editor
Article Title Intricacies during pregnancy with gestational diabetes mellitus
Manuscript Source Invited Manuscript
All Author List Richa Rattan, Rimesh Pal, Parul Chawla Gupta, Arvind Kumar Morya and Ripunjay Prasad
ORCID
Author(s) ORCID Number
Rimesh Pal http://orcid.org/0000-0003-4859-9393
Arvind Kumar Morya http://orcid.org/0000-0003-0462-119X
Funding Agency and Grant Number
Corresponding Author Arvind Kumar Morya, Professor, Department of Ophthalmology, All India Institute of Medical Sciences, Bibi Nagar, Hyderabad 508126, Telangana, India. bulbul.morya@gmail.com
Key Words Gestational diabetes mellitus; Biomarkers; Differentially expressed proteins; Retinol-binding protein 4; Angiopoietin-like 8; Proteomics; Lifestyle interventions; Early prediction
Core Tip The letter highlights certain limitations of the study by Cao et al, which explored early second-trimester biomarkers, retinol-binding protein 4 and angiopoietin-like 8, for predicting gestational diabetes mellitus (GDM). While valuable, identifying GDM in the early second trimester may not provide sufficient time for pregnant mothers to adopt major lifestyle interventions. Early first-trimester prediction or pre-conceptional identification would be more clinically significant. While the study uses advanced proteomic techniques, including isobaric tags for relative and absolute quantitation and liquid chromatography-mass spectrometry, to identify differentially expressed proteins, it is constrained by a small sample size and methodological gaps. Specifically, the reliability of protein quantification and high-abundance protein removal is unclear, and the lack of experimental validation limits the functional interpretation of identified protein interactions.
Publish Date 2024-11-07 05:10
Citation <p>Rattan R, Pal R, Gupta PC, Morya AK, Prasad R. Intricacies during pregnancy with gestational diabetes mellitus. <i>World J Clin Cases</i> 2025; 13(1): 93632</p>
URL https://www.wjgnet.com/2307-8960/full/v13/i1/93632.htm
DOI https://dx.doi.org/10.12998/wjcc.v13.i1.93632
Full Article (PDF) WJCC-13-93632-with-cover.pdf
Manuscript File 93632_Auto_Edited_053939.docx
Answering Reviewers 93632-answering-reviewers.pdf
Audio Core Tip 93632-audio.mov
Conflict-of-Interest Disclosure Form 93632-conflict-of-interest-statement.pdf
Copyright License Agreement 93632-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 93632-non-native-speakers.pdf
Peer-review Report 93632-peer-reviews.pdf
Scientific Misconduct Check 93632-scientific-misconduct-check.png
Scientific Editor Work List 93632-scientific-editor-work-list.pdf
CrossCheck Report 93632-crosscheck-report.pdf