Publication Name	World Journal of Clinical Cases
Manuscript ID	93679
Country	China

Received	2024-03-03 16:52
Peer-Review Started	2024-03-03 16:52
To Make the First Decision
Return for Revision	2024-04-22 20:01
Revised	2024-05-10 17:51
Second Decision	2024-06-06 02:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-06-07 08:57
Articles in Press	2024-06-07 08:57
Publication Fee Transferred	2024-06-13 15:17
Edit the Manuscript by Language Editor	2024-06-25 05:50
Typeset the Manuscript	2024-06-29 06:27
Publish the Manuscript Online	2024-07-02 08:41

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Respiratory System
Manuscript Type	Retrospective Study
Article Title	Study on the efficacy of early treatment with pirfenidone on lung function of idiopathic pulmonary fibrosis patients
Manuscript Source	Unsolicited Manuscript
All Author List	Ying Lei, Jian-Hui Sheng, Xu-Ru Jin, Xian-Bing Liu, Xiao-Yan Zheng and Xiao-Hua Xu
ORCID	Author(s) ORCID Number Xiao-Hua Xu http://orcid.org/0009-0005-3063-931X
Funding Agency and Grant Number
Corresponding Author	Xiao-Hua Xu, MM, Researcher, Department of Pulmonary and Critical Care Medicine, The Quzhou Affiliate Hospital of Wenzhou Medical University, No. 100 Minjiang Avenue, Quzhou 324000, Zhejiang Province, China. xxh406302383@163.com
Key Words	Pirfenidone; Early intervention; Idiopathic pulmonary fibrosis; Pulmonary function; Effect evaluation
Core Tip	The purpose of this study was to assess the effects of pirfenidone in the early treatment of idiopathic pulmonary fibrosis (IPF) on lung function in patients. A retrospective analysis was conducted on 113 patients with IPF. These patients were categorized into two groups: A control group (n = 53) and an observation group (n = 60). In the control group, patients received routine therapy in combination with methylprednisolone tablets, while the observation group received routine therapy along with pirfenidone. Eventually we came to the conclusion that the prompt initiation of pirfenidone treatment in individuals diagnosed with idiopathic pulmonary fibrosis can enhance pulmonary function, elevate inflammatory factor levels, and increase the distance covered in the 6-minute walk test. This intervention is conducive to effectively decreasing the occurrence of adverse reactions in patients.
Publish Date	2024-07-02 08:41
Citation	<p>Lei Y, Sheng JH, Jin XR, Liu XB, Zheng XY, Xu XH. Study on the efficacy of early treatment with pirfenidone on lung function of idiopathic pulmonary fibrosis patients. <i>World J Clin Cases</i> 2024; 12(22): 4913-4923</p>
URL	https://www.wjgnet.com/2307-8960/full/v12/i22/4913.htm
DOI	https://dx.doi.org/10.12998/wjcc.v12.i22.4913

Full Article (PDF)	WJCC-12-4913-with-cover.pdf
Manuscript File	93679-Review-Filipodia.docx
Answering Reviewers	93679-answering-reviewers.pdf
Audio Core Tip	93679-audio.mp3
Biostatistics Review Certificate	93679-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	93679-conflict-of-interest-statement.pdf
Copyright License Agreement	93679-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s)	93679-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	93679-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	93679-non-native-speakers.pdf
Peer-review Report	93679-peer-reviews.pdf
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Scientific Editor Work List	93679-scientific-editor-work-list.pdf
CrossCheck Report	93679-crosscheck-report.pdf