Publication Name	World Journal of Clinical Cases
Manuscript ID	9377
Country	Austria

Received	2014-02-12 10:04
Peer-Review Started	2014-02-12 21:30
To Make the First Decision	2014-03-12 16:42
Return for Revision	2014-03-20 20:41
Revised	2014-08-05 00:00
Second Decision	2014-08-29 19:02
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-08-29 19:11
Articles in Press	2014-08-29 19:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-10-14 20:06
Publish the Manuscript Online	2014-10-15 19:29

ISSN	2307-8960 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Medicine, General & Internal
Manuscript Type	Review
Article Title	Practical strategies for modulating foam cell formation and behavior
Manuscript Source	Invited Manuscript
All Author List	Elisabeth Uitz, Babak Bahadori, Mark F McCarty and Mohammed H Moghadasian
Funding Agency and Grant Number
Corresponding Author	Elisabeth Uitz, MD, Department of Internal Medicine 2, University Hospital of St. Poelten, Karl Landsteiner Private University of Health and Life Sciences, 3100 St. Poelten, Probst-Fuehrer-Str. 4, Austria. elisabeth.uitz@aon.at
Key Words	Atherosclerosis; Cholesterol; Inflammation; Phytochemical; Nutraceutical; Atherogenesis; Plaque; Cytokine; Antioxidant
Core Tip	Reverse cholesterol transport from foam cells is of key importance to prevention and control of atherosclerosis. This essay reviews the molecular biology of foam cell regulation, and proposes that certain agents may be capable of acting directly on foam cells to amplify reverse cholesterol transport while also promoting plaque stability by limiting foam cell production of inflammatory cytokines and matrix metalloproteinases. Phase 2 inducers such as lipoic acid and green tea catechins, spirulina, salicylate, taurine, and 5' adenosine monophosphate-activated protein kinase activators such as metformin or berberine, appear to have potential in this regard-while acting in additional ways to benefit vascular health.
Publish Date	2014-10-15 19:29
Citation	Uitz E, Bahadori B, McCarty MF, Moghadasian MH. Practical strategies for modulating foam cell formation and behavior. World J Clin Cases 2014; 2(10): 497-506
URL	http://www.wjgnet.com/2307-8960/full/v2/i10/497.htm
DOI	http://dx.doi.org/10.12998/wjcc.v2.i10.497

Full Article (PDF)	WJCC-2-497.pdf
Full Article (Word)	WJCC-2-497.doc
Manuscript File	9377-Review.docx
Answering Reviewers	9377-Answering reviewers.pdf
Copyright License Agreement	9377-Copyright assignment.pdf
Peer-review Report	9377-Peer review(s).pdf
Scientific Misconduct Check	9377-CrossCheck.jpg
Scientific Editor Work List	9377-Scientific editor work list.pdf