Publication Name	World Journal of Gastroenterology
Manuscript ID	9379
Country	United States

Received	2014-02-12 05:58
Peer-Review Started	2014-02-12 16:57
To Make the First Decision	2014-03-11 09:37
Return for Revision	2014-03-11 09:52
Revised	2014-03-12 08:48
Second Decision	2014-04-09 08:23
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-04-09 09:12
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-05-05 15:13
Publish the Manuscript Online	2014-05-18 12:31

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Acute pancreatitis: The stress factor
Manuscript Source	Invited Manuscript
All Author List	Marcelo G Binker and Laura I Cosen-Binker
Funding Agency and Grant Number	Funding Agency Grant Number KB Associates Representing Certification International (United Kingdom) Limited
Corresponding Author	Dr. Laura I Cosen-Binker, Department of Molecular and Cell Biology, Henry M Goldman School of Dental Medicine, Boston University, 72 East Concord Street - Evans Building - Room 408, Boston, MA 02118, United States. licb@bu.edu
Key Words	Pancreatitis; Acute stress; Chronic stress; Heat shock proteins; Tumor necrosis factor alpha
Core Tip	Depending on the timing and duration, stress can result in beneficial or harmful consequences. Regarding the exocrine pancreas, a previous acute-short-term stress decreases the severity of experimentally-induced pancreatitis. This protection is conferred by distinct heat shock proteins (HSP) including HSP27, HSP60 and HSP70. Conversely, chronic stress increases the susceptibility of the exocrine pancreas, aggravating pancreatitis episodes. These worsening effects are mainly mediated by tumor necrosis factor alpha.
Publish Date	2014-05-18 12:31
Citation	Binker MG, Cosen-Binker LI. Acute pancreatitis: The stress factor. World J Gastroenterol 2014; 20(19): 5801-5807
URL	http://www.wjgnet.com/1007-9327/full/v20/i19/5801.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i19.5801

Full Article (PDF)	WJG-20-5801.pdf
Full Article (Word)	WJG-20-5801.doc
Manuscript File	9379-review.doc
Answering Reviewers	9379-Answering Reviewers.pdf
Copyright License Agreement	9379-BPG Copyright Assignment.pdf