Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	93832
Country	Greece

Received	2024-03-06 10:15
Peer-Review Started	2024-03-06 10:15
To Make the First Decision
Return for Revision	2024-04-24 08:36
Revised	2024-05-20 22:26
Second Decision	2024-06-17 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-06-17 05:52
Articles in Press	2024-06-17 05:52
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-06-28 09:01
Typeset the Manuscript	2024-08-02 08:00
Publish the Manuscript Online	2024-08-16 15:30

ISSN	1948-9366 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Surgery
Manuscript Type	Basic Study
Article Title	Effect of growth hormone in colonic anastomosis after intraperitoneal administration of 5-fluorouracil, bleomycin and cisplatin: An experimental study
Manuscript Source	Invited Manuscript
All Author List	Ioannis Lambrou, Ioannis Mantzoros, Orestis Ioannidis, Dimitrios Tatsis, Elissavet Anestiadou, Vasiliki Bisbinas, Manousos-Georgios Pramateftakis, Efstathios Kotidis, Barbara Driagka, Ourania Kerasidou, Savvas Symeonidis, Stefanos Bitsianis, Freideriki Sifaki, Konstantinos Angelopoulos, Haralabos Demetriades and Stamatios Angelopoulos
ORCID	Author(s) ORCID Number Ioannis Lambrou http://orcid.org/0000-0002-6075-9284 Ioannis Mantzoros http://orcid.org/0000-0002-1909-4153 Orestis Ioannidis http://orcid.org/0000-0002-0861-8783 Dimitrios Tatsis http://orcid.org/0000-0003-2508-0396 Elissavet Anestiadou http://orcid.org/0000-0001-5650-7319 Vasiliki Bisbinas http://orcid.org/0000-0003-1548-0505 Manousos-Georgios Pramateftakis http://orcid.org/0000-0002-2559-2159 Efstathios Kotidis http://orcid.org/0000-0002-6729-9102 Barbara Driagka http://orcid.org/0009-0000-5686-7816 Ourania Kerasidou http://orcid.org/0009-0008-7958-8017 Savvas Symeonidis http://orcid.org/0000-0002-0096-7460 Stefanos Bitsianis http://orcid.org/0000-0001-8281-1189 Freideriki Sifaki http://orcid.org/0000-0002-5835-0797
Funding Agency and Grant Number
Corresponding Author	Orestis Ioannidis, MD, MSc, PhD, Assistant Professor, Fourth Department of Surgery, Medical School, Aristotle University of Thessaloniki, Stilponos Kyriakides 1 Str, Thessaloniki 57010, Greece. telonakos@hotmail.com
Key Words	Growth hormone; Colonic anastomosis; Adhesion; Bursting pressure; Collagen; Hydroxyproline; Inflammation; Neoangiogenesis; Chemotherapy
Core Tip	The present study was designed to investigate the effect of growth hormone (GH) in the healing of colonic anastomoses in rats after intraperitoneal administration of 5-fluorouracil, bleomycin and cisplatin. The application of GH was found to have a protective role in the healing of colonic anastomoses in rats by effectively reversing the detrimental effects of chemotherapy.
Publish Date	2024-08-16 15:30
Citation	<p>Lambrou I, Mantzoros I, Ioannidis O, Tatsis D, Anestiadou E, Bisbinas V, Pramateftakis MG, Kotidis E, Driagka B, Kerasidou O, Symeonidis S, Bitsianis S, Sifaki F, Angelopoulos K, Demetriades H, Angelopoulos S. Effect of growth hormone in colonic anastomosis after intraperitoneal administration of 5-fluorouracil, bleomycin and cisplatin: An experimental study. <i>World J Gastrointest Surg</i> 2024; 16(8): 2679-2688</p>
URL	https://www.wjgnet.com/1948-9366/full/v16/i8/2679.htm
DOI	https://dx.doi.org/10.4240/wjgs.v16.i8.2679

Full Article (PDF)	WJGS-16-2679-with-cover.pdf
Full Article (Word)	WJGS-16-2679.docx
The ARRIVE Guidelines	93832-The-ARRIVE-Guidelines.pdf
Manuscript File	93832_Auto_Edited-YJP-Language editing-Webster J-Clear.docx
Answering Reviewers	93832-answering-reviewers.pdf
Audio Core Tip	93832-audio.mp3
Biostatistics Review Certificate	93832-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	93832-conflict-of-interest-statement.pdf
Copyright License Agreement	93832-copyright-assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	93832-institutional-animal-care-and-use-committee-statement.pdf
Institutional Review Board Approval Form or Document	93832-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	93832-non-native-speakers.pdf
Peer-review Report	93832-peer-reviews.pdf
Scientific Misconduct Check	93832-scientific-misconduct-check.jpg
Scientific Editor Work List	93832-scientific-editor-work-list.pdf
CrossCheck Report	93832-crosscheck-report.pdf