| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Basic Study |
| Article Title |
Effect of growth hormone in colonic anastomosis after intraperitoneal administration of 5-fluorouracil, bleomycin and cisplatin: An experimental study
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Ioannis Lambrou, Ioannis Mantzoros, Orestis Ioannidis, Dimitrios Tatsis, Elissavet Anestiadou, Vasiliki Bisbinas, Manousos-Georgios Pramateftakis, Efstathios Kotidis, Barbara Driagka, Ourania Kerasidou, Savvas Symeonidis, Stefanos Bitsianis, Freideriki Sifaki, Konstantinos Angelopoulos, Haralabos Demetriades and Stamatios Angelopoulos |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Orestis Ioannidis, MD, MSc, PhD, Assistant Professor, Fourth Department of Surgery, Medical School, Aristotle University of Thessaloniki, Stilponos Kyriakides 1 Str, Thessaloniki 57010, Greece. telonakos@hotmail.com |
| Key Words |
Growth hormone; Colonic anastomosis; Adhesion; Bursting pressure; Collagen; Hydroxyproline; Inflammation; Neoangiogenesis; Chemotherapy |
| Core Tip |
The present study was designed to investigate the effect of growth hormone (GH) in the healing of colonic anastomoses in rats after intraperitoneal administration of 5-fluorouracil, bleomycin and cisplatin. The application of GH was found to have a protective role in the healing of colonic anastomoses in rats by effectively reversing the detrimental effects of chemotherapy. |
| Publish Date |
2024-08-16 15:30 |
| Citation |
<p>Lambrou I, Mantzoros I, Ioannidis O, Tatsis D, Anestiadou E, Bisbinas V, Pramateftakis MG, Kotidis E, Driagka B, Kerasidou O, Symeonidis S, Bitsianis S, Sifaki F, Angelopoulos K, Demetriades H, Angelopoulos S. Effect of growth hormone in colonic anastomosis after intraperitoneal administration of 5-fluorouracil, bleomycin and cisplatin: An experimental study. <i>World J Gastrointest Surg</i> 2024; 16(8): 2679-2688</p> |
| URL |
https://www.wjgnet.com/1948-9366/full/v16/i8/2679.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v16.i8.2679 |
