Publication Name	World Journal of Clinical Cases
Manuscript ID	93843
Country	China

Received	2024-03-07 08:50
Peer-Review Started	2024-03-07 08:50
To Make the First Decision
Return for Revision	2024-04-17 09:46
Revised	2024-04-22 09:11
Second Decision	2024-04-23 06:23
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-04-23 06:33
Articles in Press	2024-04-23 06:33
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-05-31 13:12
Publish the Manuscript Online	2024-06-18 09:29

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Medicine, General & Internal
Manuscript Type	Randomized Controlled Trial
Article Title	Effects of acetylcysteine on micro-inflammation and pulmonary ventilation in chronic obstructive pulmonary disease exacerbation
Manuscript Source	Unsolicited Manuscript
All Author List	Li-Yuan Huang, Bin Huang, Zheng Lv and Xiao-Dan Lu
ORCID	Author(s) ORCID Number Li-Yuan Huang http://orcid.org/0009-0007-6652-7517 Xiao-Dan Lu http://orcid.org/0000-0002-2091-2897
Funding Agency and Grant Number
Corresponding Author	Xiao-Dan Lu, PhD, Doctor, Doctor, Precision Medical Center, Jilin Province General Hospital, No. 1183, Gongnong Street, Chaoyang District, Changchun 130021, Jilin Province, China. luxiaodan@ccsfu.edu.cn
Key Words	Acute exacerbation; Chronic obstructive pulmonary disease; Traditional Chinese medicine; Acetylcysteine; Phlegm-heat and blood-stasis; Lung ventilation function
Core Tip	When used alongside conventional therapy, acetylcysteine inhalation significantly reduces inflammatory markers and improves lung function in patients with phlegm-heat and blood-stasis-type acute exacerbation of chronic obstructive pulmonary disease (AECOPD). This study highlights the potential of acetylcysteine as an effective adjunct treatment for this specific type of AECOPD, aiding in the management of microinflammation and the optimization of lung function.
Publish Date	2024-06-18 09:29
Citation	<p>Huang LY, Huang B, Lv Z, Lu XD. Effects of acetylcysteine on micro-inflammation and pulmonary ventilation in chronic obstructive pulmonary disease exacerbation. <i>World J Clin Cases</i> 2024; 12(18): 3482-3490</p>
URL	https://www.wjgnet.com/2307-8960/full/v12/i18/3482.htm
DOI	https://dx.doi.org/10.12998/wjcc.v12.i18.3482

Full Article (PDF)	WJCC-12-3482-with-cover.pdf
CONSORT 2010 Statement	93843-CONSORT-2010-statement.pdf
Manuscript File	93843_Auto_Edited-JLW.docx
Answering Reviewers	93843-answering-reviewers.pdf
Audio Core Tip	93843-audio.mp3
Biostatistics Review Certificate	93843-biostatistics-statement.pdf
Clinical Trial Registration Statement	93843-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form	93843-conflict-of-interest-statement.pdf
Copyright License Agreement	93843-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s)	93843-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	93843-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	93843-non-native-speakers.pdf
Peer-review Report	93843-peer-reviews.pdf
Scientific Misconduct Check	93843-scientific-misconduct-check.png
Scientific Editor Work List	93843-scientific-editor-work-list.pdf
CrossCheck Report	93843-crosscheck-report.png
CrossCheck Report	93843-crosscheck-report.pdf