Publication Name	World Journal of Clinical Cases
Manuscript ID	93844
Country	China

Received	2024-03-10 12:45
Peer-Review Started	2024-03-10 12:45
To Make the First Decision
Return for Revision	2024-04-17 09:45
Revised	2024-04-23 06:53
Second Decision	2024-04-28 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-04-28 09:52
Articles in Press	2024-04-28 09:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-05-27 15:44
Publish the Manuscript Online	2024-05-29 12:34

ISSN	2307-8960 (online)
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Category	Ophthalmology
Manuscript Type	Clinical and Translational Research
Article Title	Causal association between 25-hydroxyvitamin D status and cataract development: A two-sample Mendelian randomization study
Manuscript Source	Unsolicited Manuscript
All Author List	Chun-Hui Wang and Zhi-Kun Xin
ORCID	Author(s) ORCID Number Chun-Hui Wang http://orcid.org/0009-0001-9090-9423 Zhi-Kun Xin http://orcid.org/0009-0005-9515-2166
Funding Agency and Grant Number
Corresponding Author	Zhi-Kun Xin, BMed, Chief Physician, Department of Ophthalmology, Aviation General Hospital, No. 3 Anwai Beiyuan Courtyard, Anli Road, Chaoyang District, Beijing 100010, China. xzkavic@163.com
Key Words	Cataract; 25-hydroxyvitamin D; Mendelian randomization; Single nucleotide polymorphism; Causal relationship
Core Tip	Previous studies have documented the role of vitamin D in cataract development, yet investigations into the causal relationship between 25-(OH)D status and cataract onset are still lacking. Using Mendelian randomization, our study established a significant association between elevated 25-(OH)D levels and increased cataract risk. Additionally, a search of the human genotype-phenotype association database revealed no potentially relevant risk-factor single nucleotide polymorphisms. These findings need to be verified by further experiments.
Publish Date	2024-05-29 12:34
Citation	<p>Wang CH, Xin ZK. Causal association between 25-hydroxyvitamin D status and cataract development: A two-sample Mendelian randomization study. <i>World J Clin Cases</i> 2024; 12(16): 2789-2795</p>
URL	https://www.wjgnet.com/2307-8960/full/v12/i16/2789.htm
DOI	https://dx.doi.org/10.12998/wjcc.v12.i16.2789

Full Article (PDF)	WJCC-12-2789-with-cover.pdf
Manuscript File	93844_Auto_Edited-JLW.docx
Answering Reviewers	93844-Answering reviewers.pdf
Audio Core Tip	93844-Audio core tip.m4a
Biostatistics Review Certificate	93844-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	93844-Conflict-of-interest statement.pdf
Copyright License Agreement	93844-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	93844-Language certificate.pdf
Supplementary Material	93844-Supplementary material.pdf
Peer-review Report	93844-Peer-review(s).pdf
Scientific Misconduct Check	93844-Bing-Lin C-2.png
Scientific Editor Work List	93844-Scientific editor work list.pdf
CrossCheck Report	93844-CrossCheck.png
CrossCheck Report	93844-CrossCheck report.pdf