Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	93862
Country	China

Received	2024-03-06 20:51
Peer-Review Started	2024-03-06 20:51
To Make the First Decision
Return for Revision	2024-04-24 09:56
Revised	2024-05-03 09:13
Second Decision	2024-05-17 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-05-17 05:46
Articles in Press	2024-05-17 05:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-06-15 09:47
Publish the Manuscript Online	2024-07-12 15:55

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Immunology
Manuscript Type	Basic Study
Article Title	Immune effect and prognosis of transcatheter arterial chemoembolization and tyrosine kinase inhibitors therapy in patients with hepatocellular carcinoma
Manuscript Source	Unsolicited Manuscript
All Author List	Yuan Guo, Ru-Chun Li, Wei-Li Xia, Xiong Yang, Wen-Bo Zhu, Fang-Ting Li, Hong-Tao Hu and Hai-Liang Li
ORCID	Author(s) ORCID Number Hong-Tao Hu http://orcid.org/0000-0002-5432-4014 Hai-Liang Li http://orcid.org/0000-0002-4497-5649
Funding Agency and Grant Number	Funding Agency Grant Number Henan Province Natural Science Foundation 212300410403 Medical Education Research Project of Henan Province Wjlx2021334
Corresponding Author	Hai-Liang Li, MD, Chief Doctor, Department of Minimal Invasive Intervention, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, No. 127 Dongming Road, Zhengzhou 450003, Henan Province, China. lihailianggy@163.com
Key Words	Transcatheter arterial chemoembolization; Hepatocellular carcinoma; Tyrosine kinase inhibitors; Immune microenvironment; Immune responses
Core Tip	This study revealed that the combination of transcatheter arterial chemoembolization and donafinib or lenvatinib may be relatively beneficial in improving the immune suppression status of patients and inducing relatively robust anti-tumor immune responses. In addition, certain immune cells and protein molecules are significantly correlated with the prognosis of patients. The study results provide patients with reference for their selection of combination therapy strategies and help them predict their clinical prognosis.
Publish Date	2024-07-12 15:55
Citation	<p>Guo Y, Li RC, Xia WL, Yang X, Zhu WB, Li FT, Hu HT, Li HL. Immune effect and prognosis of transcatheter arterial chemoembolization and tyrosine kinase inhibitors therapy in patients with hepatocellular carcinoma. <i>World J Gastrointest Oncol</i> 2024; 16(7): 3256-3269</p>
URL	https://www.wjgnet.com/1948-5204/full/v16/i7/3256.htm
DOI	https://dx.doi.org/10.4251/wjgo.v16.i7.3256

Full Article (PDF)	WJGO-16-3256-with-cover.pdf
The ARRIVE Guidelines	93862-The-ARRIVE-Guidelines.pdf
Manuscript File	93862_Auto_Edited-YJP.docx
Answering Reviewers	93862-answering-reviewers.pdf
Audio Core Tip	93862-audio.mp3
Biostatistics Review Certificate	93862-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	93862-conflict-of-interest-statement.pdf
Copyright License Agreement	93862-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	93862-foundation-statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document	93862-institutional-animal-care-and-use-committee-statement.pdf
Institutional Review Board Approval Form or Document	93862-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	93862-non-native-speakers.pdf
Peer-review Report	93862-peer-reviews.pdf
Scientific Misconduct Check	93862-scientific-misconduct-check.png
Scientific Misconduct Check	93862-scientific-misconduct-check.png
Scientific Editor Work List	93862-scientific-editor-work-list.pdf
CrossCheck Report	93862-crosscheck-report.pdf