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Publication Name World Journal of Gastroenterology
Manuscript ID 940
Country Japan
Received
2012-10-29 15:54
Peer-Review Started
2012-10-29 22:00
To Make the First Decision
2012-11-07 17:55
Return for Revision
2012-11-12 18:10
Revised
2012-11-15 00:11
Second Decision
2013-03-06 17:52
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-03-07 06:55
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-04-01 11:08
Publish the Manuscript Online
2013-04-19 20:40
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Dipeptidyl peptidase-4: A key player in chronic liver disease
Manuscript Source Invited Manuscript
All Author List Minoru Itou, Takumi Kawaguchi, Eitaro Taniguchi and Michio Sata
Funding Agency and Grant Number
Corresponding Author Takumi Kawaguchi, MD, PhD, Division of Gastroenterology, Department of Medicine and Department of Digestive Disease Information and Research, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011, Japan. takumi@med.kurume-u.ac.jp
Key Words Incretin; Viral hepatitis; Insulin resistance; Steatohepatitis; Cancer; Sitagliptin; Vildagliptin; Alogliptin; Teneligliptin; Linagliptin
Core Tip Dipeptidyl peptidase-4 (DPP-4) is a membrane-associated peptidase, also known as CD26. DPP-4 has widespread organ distribution throughout the body and exerts pleiotropic effects via its peptidase activity. In this review, we described the tissue distribution and various biological effects of DPP-4. Then, we discussed the impact of DPP-4 in chronic liver disease and the possible therapeutic effects of a DPP-4 inhibitor.
Publish Date 2013-04-19 20:40
Citation Itou M, Kawaguchi T, Taniguchi E, Sata M. Dipeptidyl peptidase-4: A key player in chronic liver disease. World J Gastroenterol 2013; 19(15): 2298-2306
URL http://www.wjgnet.com/1007-9327/full/v19/i15/2298.htm
DOI http://dx.doi.org/10.3748/wjg.v19.i15.2298
Full Article (PDF) WJG-19-2298.pdf
Manuscript File 940-Review.doc
Answering Reviewers 940-Answering reviewers.doc
Copyright License Agreement 940-Copyright assignment.doc
Non-Native Speakers of English Editing Certificate 940-Language certificate.pdf
Peer-review Report 940-Peer review(s).docx
Scientific Editor Work List 940-Scientific editor work list.doc