Publication Name	World Journal of Clinical Cases
Manuscript ID	94024
Country	Taiwan

Received	2024-03-10 01:53
Peer-Review Started	2024-03-10 01:53
To Make the First Decision
Return for Revision	2024-06-20 03:06
Revised	2024-07-02 07:25
Second Decision	2024-07-17 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-07-17 09:23
Articles in Press	2024-07-17 09:23
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-07-18 10:28
Typeset the Manuscript	2024-08-23 06:38
Publish the Manuscript Online	2024-09-04 06:40

ISSN	2307-8960 (online)
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Category	Medical Informatics
Manuscript Type	Editorial
Article Title	Unraveling autophagy-related pathogenesis in active ulcerative colitis: A bioinformatics approach
Manuscript Source	Invited Manuscript
All Author List	Wen-Rui Hao, Chun-Yao Cheng, Ju-Chi Liu and Tzu-Hurng Cheng
ORCID	Author(s) ORCID Number Tzu-Hurng Cheng http://orcid.org/0000-0002-9155-4169
Funding Agency and Grant Number
Corresponding Author	Tzu-Hurng Cheng, PhD, Professor, Department of Biochemistry, School of Medicine, College of Medicine, China Medical University, No. 91 Xueshi Road, North District, Taichung City 404333, Taiwan. thcheng@mail.cmu.edu.tw
Key Words	Ulcerative colitis; Autophagy; Bioinformatics; Pathogenesis; Therapeutic targets
Core Tip	Gong et al’s study highlights HSPA5, CASP1, SERPINA1, CX3CL1, and BAG3 as core autophagy-related targets upregulated in active ulcerative colitis (UC) patients. Enrichment analysis underscores the involvement of autophagy in key signaling pathways and diseases associated with UC. Immune cell infiltration analysis emphasizes the importance of immune dysregulation in UC progression. These findings provide crucial insights into the molecular mechanisms underlying UC pathogenesis and may guide the development of personalized treatment strategies for UC patients.
Publish Date	2024-09-04 06:40
Citation	<p>Hao WR, Cheng CY, Liu JC, Cheng TH. Unraveling autophagy-related pathogenesis in active ulcerative colitis: A bioinformatics approach. <i>World J Clin Cases</i> 2024; 12(30): 6335-6338</p>
URL	https://www.wjgnet.com/2307-8960/full/v12/i30/6335.htm
DOI	https://dx.doi.org/10.12998/wjcc.v12.i30.6335

Full Article (PDF)	WJCC-12-6335-with-cover.pdf
Manuscript File	94024_Auto_Edited_063437.docx
Answering Reviewers	94024-answering-reviewers.pdf
Audio Core Tip	94024-audio.mp3
Conflict-of-Interest Disclosure Form	94024-conflict-of-interest-statement.pdf
Copyright License Agreement	94024-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	94024-non-native-speakers.pdf
Peer-review Report	94024-peer-reviews.pdf
Scientific Misconduct Check	94024-scientific-misconduct-check.png
Scientific Editor Work List	94024-scientific-editor-work-list.pdf
CrossCheck Report	94024-crosscheck-report.pdf
CrossCheck Report	94024-crosscheck-report.png