Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	94039
Country	China

Received	2024-03-12 05:13
Peer-Review Started	2024-03-12 05:13
To Make the First Decision
Return for Revision	2024-06-04 02:20
Revised	2024-06-08 12:46
Second Decision	2024-07-08 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-07-08 06:31
Articles in Press	2024-07-08 06:31
Publication Fee Transferred	2024-07-13 10:39
Edit the Manuscript by Language Editor	2024-07-24 02:12
Typeset the Manuscript	2024-07-31 09:34
Publish the Manuscript Online	2024-08-16 15:30

ISSN	1948-9366 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/
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Category	Anesthesiology
Manuscript Type	Randomized Clinical Trial
Article Title	Application value of dexmedetomidine in anesthesia for elderly patients undergoing radical colon cancer surgery
Manuscript Source	Unsolicited Manuscript
All Author List	Hui-Min Bu, Min Zhao, Hong-Mei Ma and Xiao-Peng Tian
ORCID	Author(s) ORCID Number Hui-Min Bu http://orcid.org/0009-0006-9560-1205 Min Zhao http://orcid.org/0009-0008-5182-0574 Hong-Mei Ma http://orcid.org/0009-0006-7409-7839 Xiao-Peng Tian http://orcid.org/0009-0000-0980-7861
Funding Agency and Grant Number
Corresponding Author	Xiao-Peng Tian, MA, Attending Doctor, Department of Anesthesia Surgery, Qingdao Haici Hospital Affiliated to Qingdao University (Qingdao Hospital of Traditional Chinese Medicine), No. 4 Renmin Road, Shibei District, Qingdao 266033, Shandong Province, China. txp21359079@163.com
Key Words	Colon cancer; Dexmedetomidine; General anesthesia; Elderly; Radical colon cancer surgery; Bispectral index; Cognitive function; Regional cerebral oxygen saturation
Core Tip	This study aimed to explore the impact and significance of dexmedetomidine (Dex) as an adjunct to general anesthesia on bispectral index, cognitive function, and local brain oxygen saturation in elderly patients undergoing radical colon cancer surgery. The use of Dex as an adjunct to general anesthesia in elderly patients undergoing radical colon cancer surgery helps maintain regional cerebral oxygen saturation levels and reduce cerebral metabolic levels, thereby lowering the incidence of anesthesia- and surgery-induced cognitive dysfunction and reducing the dosage of related anesthetic drugs.
Publish Date	2024-08-16 15:30
Citation	<p>Bu HM, Zhao M, Ma HM, Tian XP. Application value of dexmedetomidine in anesthesia for elderly patients undergoing radical colon cancer surgery. <i>World J Gastrointest Surg</i> 2024; 16(8): 2671-2678</p>
URL	https://www.wjgnet.com/1948-9366/full/v16/i8/2671.htm
DOI	https://dx.doi.org/10.4240/wjgs.v16.i8.2671

Full Article (PDF)	WJGS-16-2671-with-cover.pdf
Full Article (Word)	WJGS-16-2671.docx
CONSORT 2010 Statement	94039-CONSORT-2010-statement.pdf
Manuscript File	94039_Auto_Edited_070956.docx
Answering Reviewers	94039-answering-reviewers.pdf
Audio Core Tip	94039-audio.m4a
Biostatistics Review Certificate	94039-biostatistics-statement.pdf
Clinical Trial Registration Statement	94039-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form	94039-conflict-of-interest-statement.pdf
Copyright License Agreement	94039-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s)	94039-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	94039-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	94039-non-native-speakers.pdf
Peer-review Report	94039-peer-reviews.pdf
Scientific Misconduct Check	94039-scientific-misconduct-check.png
Scientific Editor Work List	94039-scientific-editor-work-list.pdf
CrossCheck Report	94039-crosscheck-report.pdf
CrossCheck Report	94039-crosscheck-report.png