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Articles Published Processes
8/16/2024 3:30:03 PM | Browse: 70 | Download: 205
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Received |
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2024-03-10 13:56 |
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Peer-Review Started |
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2024-03-10 13:56 |
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To Make the First Decision |
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Return for Revision |
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2024-04-29 01:39 |
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Revised |
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2024-05-05 12:24 |
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Second Decision |
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2024-06-03 02:40 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-06-03 06:04 |
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Articles in Press |
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2024-06-03 06:04 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2024-06-04 13:55 |
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Typeset the Manuscript |
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2024-07-01 09:03 |
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Publish the Manuscript Online |
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2024-08-16 15:30 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Editorial |
| Article Title |
Consideration on immunotherapy of liver metastases of malignant tumors
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Chuang Jiang, Zhi-Hong Zhang and Jia-Xin Li |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Project of Guizhou Provincial Department of Science and Technology, No. Qian Ke He Cheng Guo |
LC[2024]109 |
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| Corresponding Author |
Jia-Xin Li, MD, Assistant Professor, Chief Doctor, Division of Liver Surgery, Department of General Surgery and Laboratory of Liver Surgery, and State Key Laboratory of Biotherapy and Collaborative Innovation Center of Biotherapy, West China Hospital, Sichuan University, No. 37 Guo Xue Alley, Chengdu 610041, Sichuan Province, China. lijiaxin@scu.edu.cn |
| Key Words |
Liver metastasis; Immunotherapy; Immune tolerance; Cancer; Treatment |
| Core Tip |
Immunotherapy is an important treatment method for solid tumors nowadays. However, liver metastasis leads to a decrease in the efficacy of immunotherapy for malignant tumors. The main reason is that liver metastasis can promote the depletion of systemic CD8(+) T cells by utilizing the host's peripheral immune tolerance mechanism, thereby leading to a systemic immune tolerance environment. In the dilemma of limited efficacy of immunotherapy alone, the combination of chemotherapy, radiotherapy, targeted therapy, and other anti-tumor methods can significantly enhance the efficacy of immunotherapy, holding important clinical prospects. |
| Publish Date |
2024-08-16 15:30 |
| Citation |
<p>Jiang C, Zhang ZH, Li JX. Consideration on immunotherapy of liver metastases of malignant tumors. <i>World J Gastrointest Surg</i> 2024; 16(8): 2374-2381</p> |
| URL |
https://www.wjgnet.com/1948-9366/full/v16/i8/2374.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v16.i8.2374 |
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