Publication Name	World Journal of Clinical Oncology
Manuscript ID	94097
Country	China

Received	2024-03-11 08:43
Peer-Review Started	2024-03-11 08:43
To Make the First Decision
Return for Revision	2024-05-11 08:33
Revised	2024-05-21 09:13
Second Decision	2024-06-05 02:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-06-05 07:52
Articles in Press	2024-06-05 07:52
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-06-12 13:40
Typeset the Manuscript	2024-06-21 01:21
Publish the Manuscript Online	2024-07-16 06:17

ISSN	2218-4333 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Case Report
Article Title	Concomitant epidermal growth factor receptor mutation/c-ros oncogene 1 rearrangement in non-small cell lung cancer: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Gui-Qin Peng, Hai-Chi Song and Wan-Yi Chen
ORCID	Author(s) ORCID Number Hai-Chi Song http://orcid.org/0009-0002-9622-9530 Wan-Yi Chen http://orcid.org/0000-0002-6151-6890
Funding Agency and Grant Number	Funding Agency Grant Number Wu Jieping Medical Foundation 320.6750.2022.20.25 Chongqing Health Commission ﹝2020﹞68
Corresponding Author	Wan-Yi Chen, MSc, Associate Chief Pharmacist, Department of Pharmacy, Chongqing University Cancer Hospital, No. 181 Hanyu Road, Shapingba District, Chongqing 400030, China. wanyichen_cquch@163.com
Key Words	Non-small cell lung cancer; Epidermal growth factor receptor; C-ros oncogene 1; Co-mutation; Treatment strategies; Case report
Core Tip	Over the past two decades, molecular targeted therapies have improved clinical outcomes significantly for non-small cell lung cancer (NSCLC) patients with both epidermal growth factor receptor (EGFR) mutation and c-ros oncogene 1 (ROS1) fusion. Nevertheless, EGFR/ROS1 co-mutation is a rare event in NSCLC, and the standard treatment for such cases is still equivocal. We reported an EGFR/ROS1 co-mutation in an NSCLC patient who remained clinically stable after 53 months of treatment with crizotinib. This is the longest progression-free survival reported in the literature. This case suggested that crizotinib may be a potential choice for NSCLC patients with the EGFR/ROS1 co-mutation.
Publish Date	2024-07-16 06:17
Citation	<p>Peng GQ, Song HC, Chen WY. Concomitant epidermal growth factor receptor mutation/c-ros oncogene 1 rearrangement in non-small cell lung cancer: A case report. <i>World J Clin Oncol</i> 2024; 15(7): 945-952</p>
URL	https://www.wjgnet.com/2218-4333/full/v15/i7/945.htm
DOI	https://dx.doi.org/10.5306/wjco.v15.i7.945

Full Article (PDF)	WJCO-15-945-with-cover.pdf
CARE Checklist–2016	94097-CARE-Checklist-2016.pdf
Manuscript File	94097_Auto_Edited-YJP_WangTQ.docx
Answering Reviewers	94097-answering-reviewers.pdf
Audio Core Tip	94097-audio.mp3
Conflict-of-Interest Disclosure Form	94097-conflict-of-interest-statement.pdf
Copyright License Agreement	94097-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	94097-foundation-statement.pdf
Signed Consent for Treatment Form(s) or Document(s)	94097-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate	94097-non-native-speakers.pdf
Peer-review Report	94097-peer-reviews.pdf
Scientific Misconduct Check	94097-scientific-misconduct-check.jpg
Scientific Editor Work List	94097-scientific-editor-work-list.pdf
CrossCheck Report	94097-crosscheck-report.pdf