Publication Name	World Journal of Gastroenterology
Manuscript ID	94104
Country	China

Received	2024-03-11 10:53
Peer-Review Started	2024-03-11 10:53
To Make the First Decision
Return for Revision	2024-06-29 04:22
Revised	2024-07-11 16:35
Second Decision	2024-08-02 02:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-08-02 06:02
Articles in Press	2024-08-02 06:02
Publication Fee Transferred	2024-08-02 09:51
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-08-06 07:56
Publish the Manuscript Online	2024-08-13 08:00

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Prospective Study
Article Title	Alterations in the gut microbiome after transjugular intrahepatic portosystemic shunt in patients with hepatitis B virus-related portal hypertension
Manuscript Source	Unsolicited Manuscript
All Author List	Hong-Wei Zhao, Jin-Long Zhang, Fu-Quan Liu, Zhen-Dong Yue, Lei Wang, Yu Zhang, Cheng-Bin Dong and Zhen-Chang Wang
ORCID	Author(s) ORCID Number Hong-Wei Zhao http://orcid.org/0000-0001-6409-5537 Fu-Quan Liu http://orcid.org/0000-0003-1972-7712 Zhen-Dong Yue http://orcid.org/0000-0001-5403-8336 Lei Wang http://orcid.org/0000-0002-4374-059X Cheng-Bin Dong http://orcid.org/0000-0003-1643-1460 Zhen-Chang Wang http://orcid.org/0000-0001-8190-6469
Funding Agency and Grant Number
Corresponding Author	Zhen-Chang Wang, MD, Professor, Department of Radiology, Beijing Friendship Hospital, Capital Medical University, No. 95 Yongan Road, Xicheng District, Beijing 100050, China. cjr.wzhch@vip.163.com
Key Words	Transjugular intrahepatic portosystemic shunt; Hepatic encephalopathy; Gut microbiota; Hepatitis B virus; Portal hypertension
Core Tip	Gut microbiota (GM) alterations have been demonstrated in patients with portal hypertension, influencing hepatic encephalopathy (HE) development. The present study analyzes the changes in GM composition in Chinese patients with hepatitis B virus related portal hypertension before and after transjugular intrahepatic portosystemic shunt (TIPS). The results revealed that patients without HE exhibited higher GM-related synergism than those with HE, regardless of TIPS placement. Thus, the synergism of intestinal microbiota may serve as a useful indicator to predict the risk of HE after TIPS placement.
Publish Date	2024-08-13 08:00
Citation	<p>Zhao HW, Zhang JL, Liu FQ, Yue ZD, Wang L, Zhang Y, Dong CB, Wang ZC. Alterations in the gut microbiome after transjugular intrahepatic portosystemic shunt in patients with hepatitis B virus-related portal hypertension. <i>World J Gastroenterol</i> 2024; 30(31): 3668-3679</p>
URL	https://www.wjgnet.com/1007-9327/full/v30/i31/3668.htm
DOI	https://dx.doi.org/10.3748/wjg.v30.i31.3668

Full Article (PDF)	WJG-30-3668-with-cover.pdf
CONSORT 2010 Statement	94104-CONSORT-2010-statement.pdf
Manuscript File	94104_Auto_Edited_063209.docx
Answering Reviewers	94104-answering-reviewers.pdf
Audio Core Tip	94104-audio.mp3
Biostatistics Review Certificate	94104-biostatistics-statement.pdf
Clinical Trial Registration Statement	94104-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form	94104-conflict-of-interest-statement.pdf
Copyright License Agreement	94104-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s)	94104-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	94104-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	94104-non-native-speakers.pdf
Supplementary Material	94104-supplementary-material.pdf
Peer-review Report	94104-peer-reviews.pdf
Scientific Misconduct Check	94104-scientific-misconduct-check.png
Scientific Editor Work List	94104-scientific-editor-work-list.pdf
CrossCheck Report	94104-crosscheck-report.pdf