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6/13/2024 2:30:26 AM | Browse: 90 | Download: 263
Publication Name World Journal of Orthopedics
Manuscript ID 94266
Country Pakistan
Received
2024-03-14 12:12
Peer-Review Started
2024-03-18 02:49
To Make the First Decision
Return for Revision
2024-04-17 04:52
Revised
2024-05-02 10:18
Second Decision
2024-05-22 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2024-05-22 08:34
Articles in Press
2024-05-22 08:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2024-05-29 08:13
Publish the Manuscript Online
2024-06-13 02:30
ISSN 2218-5836 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: Https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Orthopedics
Manuscript Type Letter to the Editor
Article Title Carbamazepine in osteoarthritis treatment: A novel approach targeting Nav1.7 channels
Manuscript Source Invited Manuscript
All Author List Rayyan Vaid, Afra Sohail and Nabiha Amir
ORCID
Author(s) ORCID Number
Rayyan Vaid http://orcid.org/0000-0002-0384-700X
Funding Agency and Grant Number
Corresponding Author Rayyan Vaid, MBBS, Academic Fellow, Academic Research, Department of Medicine, Karachi Medical and Dental College, Lane 10, Karachi 75500, Pakistan. rayyanvaid222@gmail.com
Key Words Osteoarthritis; Joint illness; Treatment approaches; Pain management; Healthcare expenses
Core Tip Carbamazepine, a non-specific voltage-gated sodium channel blocker primarily used for epilepsy, has shown promising results in preclinical studies for treating osteoarthritis (OA). By targeting Nav1.7 channels, it not only reduces pain but also protects against joint degradation by modulating chondrocyte biology. However, further research is needed to confirm its efficacy in humans, potentially paving the way for innovative OA treatments beyond traditional analgesics.
Publish Date 2024-06-13 02:30
Citation <p>Vaid R, Sohail A, Amir N. Carbamazepine in osteoarthritis treatment: A novel approach targeting Nav1.7 channels. <i>World J Orthop</i> 2024; 15(6): 602-604</p>
URL https://www.wjgnet.com/2218-5836/full/v15/i6/602.htm
DOI https://dx.doi.org/10.5312/wjo.v15.i6.602
Full Article (PDF) WJO-15-602-with-cover.pdf
Manuscript File 94266_Auto_Edited-YJP.docx
Answering Reviewers 94266-answering-reviewers.pdf
Audio Core Tip 94266-audio.mp3
Conflict-of-Interest Disclosure Form 94266-conflict-of-interest-statement.pdf
Copyright License Agreement 94266-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 94266-non-native-speakers.pdf
Peer-review Report 94266-peer-reviews.pdf
Scientific Misconduct Check 94266-scientific-misconduct-check.png
Scientific Editor Work List 94266-scientific-editor-work-list.pdf
CrossCheck Report 94266-crosscheck-report.png
CrossCheck Report 94266-crosscheck-report.pdf