| Category |
Health Care Sciences & Services |
| Manuscript Type |
Minireviews |
| Article Title |
Genetic and environmental determinants of risk for cholangiocarcinoma in Thailand
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Masanao Miwa, Satoshi Honjo, Gyokukou You, Masakazu Tanaka, Kazuhiko Uchida, Petcharin Srivatanakul, Thiravud Khuhaprema, Watcharin Loilome, Anchalee Techasen, Chaisiri Wongkham, Temduang Limpaiboon, Puangrat Yongvanit and Sopit Wongkham |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology Japan |
|
|
| Corresponding Author |
Masanao Miwa, MD, PhD, Nagahama Institute of Bio-Science and Technology, Nagahama, Shiga 526-0829, Japan. m_miwa@nagahama-i-bio.ac.jp |
| Key Words |
Thailand; Opisthorchis viverrini; Liver fluke; 8-oxoguanine glycosylase 1; Glutathione S transferase; DNA polymorphism; Cholangiocarcinoma; Alcohol drinking |
| Core Tip |
Cholangiocarcinoma (CCA) is an intractable cancer due to the difficulty of diagnosis in its early stage. The incidence of CCA in the northeast of Thailand is the highest in the world. It is of the utmost importance to analyze the risk factors and the mechanism to prevent the disease and to also detect the disease in its early stage to save patients’ lives. We analyzed the genetic and environmental determinants of risks for CCA and discussed this with the findings already published by other researchers. It is of the utmost importance to develop a non-invasive, specific and sensitive method to detect CCA. |
| Publish Date |
2014-11-19 10:25 |
| Citation |
Miwa M, Honjo S, You G, Tanaka M, Uchida K, Srivatanakul P, Khuhaprema T, Loilome W, Techasen A, Wongkham C, Limpaiboon T, Yongvanit P, Wongkham S. Genetic and environmental determinants of risk for cholangiocarcinoma in Thailand. World J Gastrointest Pathophysiol 2014; 5(4): 570-578 |
| URL |
http://www.wjgnet.com/2150-5330/full/v5/i4/570.htm |
| DOI |
http://dx.doi.org/10.4291/wjgp.v5.i4.570 |
