Publication Name	World Journal of Clinical Cases
Manuscript ID	94330
Country	China

Received	2024-03-15 14:58
Peer-Review Started	2024-03-15 14:58
To Make the First Decision
Return for Revision	2024-09-15 18:44
Revised	2024-09-28 19:06
Second Decision	2024-11-05 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-11-05 09:57
Articles in Press	2024-11-05 09:57
Publication Fee Transferred	2024-10-23 13:29
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-11-18 01:21
Publish the Manuscript Online	2024-11-25 09:10

ISSN	2307-8960 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Hydroxyurea-related ileocecal region ulcers as a rare complication: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Wen-Jin Yuan, Yi-Juan Zheng, Bing-Rong Zhang, Yi-Jie Lin, You Li, Yan-Yan Qiu and Xue-Ping Yu
ORCID	Author(s) ORCID Number Xue-Ping Yu http://orcid.org/0000-0002-1157-2501
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China No. 82370604 Major Science and Technology innovation Project of Fujian Province No. 2023Y9269 Natural Science Foundation of Fujian Province, China No. 2023J01239
Corresponding Author	Xue-Ping Yu, MD, PhD, Department of Infection Disease, Clinical Medical Research Center for Bacterial and Fungal Infectious Diseases of Fujian province, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou 362000, Fujian Province, China. xpyu15@fudan.edu.cn
Key Words	Hydroxyurea; Ulcer; Abdominal pain; Thrombocythemia; Colonoscopy; Case report
Core Tip	Ileocecal ulcers related to hydroxyurea are a rare adverse reaction and may be associated with drug hypersensitivity vasculitis and Behcet's disease. However, its specific pathogenic mechanism remains unknown. To date, only four cases of ileocecal ulcers have been reported worldwide, including three cases of the condition being complicated by pyrexia/fever, oral ulcers, and xerosis cutis. Pathological findings of ileocecal ulcers in these four cases revealed inflammatory changes that improved after hydroxyurea was discontinued. This report aims to raise awareness of the rare complication of hydroxyurea-induced ileocecal ulcers.
Publish Date	2024-11-25 09:10
Citation	<p>Yuan WJ, Zheng YJ, Zhang BR, Lin YJ, Li Y, Qiu YY, Yu XP. Hydroxyurea-related ileocecal region ulcers as a rare complication: A case report. <i>World J Clin Cases</i> 2025; 13(6): 94330</p>
URL	https://www.wjgnet.com/2307-8960/full/v13/i6/94330.htm
DOI	https://dx.doi.org/10.12998/wjcc.v13.i6.94330

Full Article (PDF)	WJCC-13-94330-with-cover.pdf
CARE Checklist–2016	94330-CARE-Checklist-2016.pdf
Manuscript File	94330_Auto_Edited_054953.docx
Answering Reviewers	94330-answering-reviewers.pdf
Audio Core Tip	94330-audio.mp3
Conflict-of-Interest Disclosure Form	94330-conflict-of-interest-statement.pdf
Copyright License Agreement	94330-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	94330-foundation-statement.pdf
Signed Consent for Treatment Form(s) or Document(s)	94330-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate	94330-non-native-speakers.pdf
Peer-review Report	94330-peer-reviews.pdf
Scientific Misconduct Check	94330-scientific-misconduct-check.png
Scientific Editor Work List	94330-scientific-editor-work-list.pdf
CrossCheck Report	94330-crosscheck-report.pdf