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Articles Published Processes
7/26/2024 6:56:09 AM | Browse: 48 | Download: 149
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Received |
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2024-03-15 19:36 |
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Peer-Review Started |
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2024-03-15 19:36 |
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To Make the First Decision |
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Return for Revision |
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2024-05-15 22:20 |
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2024-05-26 19:08 |
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Second Decision |
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2024-06-06 02:48 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-06-06 06:57 |
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Articles in Press |
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2024-06-06 06:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-06-13 08:56 |
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Publish the Manuscript Online |
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2024-07-26 06:56 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Editorial |
| Article Title |
Diabetic cardiomyopathy: Importance of direct evidence to support the roles of NOD-like receptor protein 3 inflammasome and pyroptosis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Lu Cai, Yi Tan, Md Shahidul Islam, Michael Horowitz and Kupper A Wintergerst |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Lu Cai, MD, PhD, Director, Director, Professor, Pediatric Research Institute, Departments of Pediatrics, Radiation Oncology, Pharmacology and Toxicology, University of Louisville, Wendy Novak Diabetes Institute, Norton Children’s Hospital,, 570 S. Preston Street, Baxter I, Rm: 304F, Louisville, KY 40202, United States. lu.cai@louisville.edu |
| Key Words |
Diabetic cardiomyopathy; Nucleotide oligomerization domain; NOD-like receptor protein 3 inflammasome; Cardiac cell death; Pyroptosis |
| Core Tip |
The involvement of the NOD-like receptor protein 3 (NLRP3) inflammasome and pyroptosis in the pathogenesis of diabetic cardiomyopathy (DCM) has been extensively explored. However, most studies focused on whether diabetes causes NLRP3 inflammasome activation and pyroptosis in the diabetic heart, as well as the potential of medications and natural products to mitigate DCM progression along with reducing NLRP3 inflammasome expression and pyroptosis. Few studies directly investigated the roles of NLRP3 inflammasome and pyroptosis in the development of DCM, utilizing appropriate approaches, such as NLRP3 gene silencing or pharmaceutical NLRP3 inhibitors. Therefore, this aspect of investigation is an urgent need, as stated in this editorial. |
| Publish Date |
2024-07-26 06:56 |
| Citation |
<p>Cai L, Tan Y, Islam MS, Horowitz M, Wintergerst KA. Diabetic cardiomyopathy: Importance of direct evidence to support the roles of NOD-like receptor protein 3 inflammasome and pyroptosis. <i>World J Diabetes</i> 2024; 15(8): 1659-1662</p> |
| URL |
https://www.wjgnet.com/1948-9358/full/v15/i8/1659.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v15.i8.1659 |
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