Publication Name	World Journal of Clinical Cases
Manuscript ID	94369
Country	China

Received	2024-03-17 13:35
Peer-Review Started	2024-03-17 13:35
To Make the First Decision
Return for Revision	2024-05-07 19:22
Revised	2024-05-13 05:49
Second Decision	2024-05-28 02:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-05-28 08:15
Articles in Press	2024-05-28 08:15
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-06-10 01:52
Typeset the Manuscript	2024-06-28 06:44
Publish the Manuscript Online	2024-07-01 13:38

ISSN	2307-8960 (online)
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Retrospective Study
Article Title	Relationship of inflammatory indices with left atrial appendage thrombus or spontaneous echo contrast in patients with atrial fibrillation
Manuscript Source	Unsolicited Manuscript
All Author List	Zhao Wang, Bin-Hao Wang, Xiao-Lei Yang, Yun-Long Xia, Sheng-Min Zhang and Ying Che
ORCID	Author(s) ORCID Number Zhao Wang http://orcid.org/0000-0003-3074-4492 Bin-Hao Wang http://orcid.org/0000-0001-5341-3878 Xiao-Lei Yang http://orcid.org/0000-0002-6132-5971 Yun-Long Xia http://orcid.org/0000-0001-7985-3273 Sheng-Min Zhang http://orcid.org/0000-0003-3178-0313 Ying Che http://orcid.org/0000-0002-0044-4168
Funding Agency and Grant Number	Funding Agency Grant Number Public Welfare Technology Project of Ningbo Science and Technology Bureau 2023S140 Medical Health Science and Technology Project of Zhejiang Province Health Commission 2024KY1518
Corresponding Author	Ying Che, MD, Professor, Department of Ultrasonography, First Affiliated Hospital of Dalian Medical University, No. 222 Zhongshan Road, Dalian 116000, Liaoning Province, China. cheying@dmu.edu.cn
Key Words	Nonvalvular atrial fibrillation; Left atrial appendage thrombus; Spontaneous echo contrast; Neutrophil–lymphocyte ratio; Lymphocyte–monocyte ratio
Core Tip	Atrial fibrillation (AF) increases the risk of ischemic stroke. One of the most powerful risk factors for ischemic stroke is the development of a thrombus and spontaneous echo contrast (SEC) in the left atrial appendage (LAA). Inflammatory state increases the propensity for thrombosis in AF patients. Therefore, we explored the value of inflammatory indices for predicting the presence of LAA thrombus or dense SEC. The results showed that some inflammatory indices derived from complete blood tests, including neutrophil-lymphocyte ratio and lymphocyte-monocyte ratio, may predict LAA thrombus or dense SEC in patients with nonvalvular AF.
Publish Date	2024-07-01 13:38
Citation	<p>Wang Z, Wang BH, Yang XL, Xia YL, Zhang SM, Che Y. Relationship of inflammatory indices with left atrial appendage thrombus or spontaneous echo contrast in patients with atrial fibrillation. <i>World J Clin Cases</i> 2024; 12(21): 4550-4557</p>
URL	https://www.wjgnet.com/2307-8960/full/v12/i21/4550.htm
DOI	https://dx.doi.org/10.12998/wjcc.v12.i21.4550

Full Article (PDF)	WJCC-12-4550-with-cover.pdf
Manuscript File	94369_Auto_Edited_WangTQ.docx
Answering Reviewers	94369-answering-reviewers.pdf
Audio Core Tip	94369-audio.mp3
Biostatistics Review Certificate	94369-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	94369-conflict-of-interest-statement.pdf
Copyright License Agreement	94369-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	94369-foundation-statement.pdf
Signed Informed Consent Form(s) or Document(s)	94369-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	94369-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	94369-non-native-speakers.pdf
Peer-review Report	94369-peer-reviews.pdf
Scientific Misconduct Check	94369-scientific-misconduct-check.jpg
Scientific Editor Work List	94369-scientific-editor-work-list.pdf
CrossCheck Report	94369-crosscheck-report.pdf