Publication Name	World Journal of Gastroenterology
Manuscript ID	9443
Country	Sweden

Received	2014-02-12 05:39
Peer-Review Started	2014-02-12 09:24
To Make the First Decision	2014-03-13 19:02
Return for Revision	2014-03-20 10:12
Revised	2014-04-12 17:29
Second Decision	2014-05-26 16:27
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-05-26 16:55
Articles in Press	2014-05-26 17:31
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-07-10 09:08
Publish the Manuscript Online	2014-07-26 13:36

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Surgery
Manuscript Type	Autobiography
Article Title	Conventional, but not remote ischemic preconditioning, reduces iNOS transcription in liver ischemia/reperfusion
Manuscript Source	Unsolicited Manuscript
All Author List	Bergthor Björnsson, Anders Winbladh, Linda Bojmar, Tommy Sundqvist, Per Gullstrand and Per Sandström
Funding Agency and Grant Number	Funding Agency Grant Number Gösta Milton Donation Fund (Partly)
Corresponding Author	Bergthor Bj?rnsson, MD, Department of Surgery, County Council of ?sterg?tland, 581 85 Link?ping, Sweden. bergthor.bjornsson@lio.se
Key Words	Ischemia-reperfusion injury; Preconditioning; Remote preconditioning; Liver ischemia; Liver surgery; Microdialysis; Nitric oxide; Inducible nitric oxide synthase; Interleukin-1 receptor
Core Tip	Ischemic preconditioning has been shown to reduce ischemia/reperfusion injury (IRI) in the liver. NO has been shown to be important in the preconditioning process as well as in IRI. This study shows that ischemic preconditioning (IPC) but not remote ischemic preconditioning (R-IPC) reduces inducible nitric oxide synthase and interleukin 1 receptor transcription during early reperfusion. As it has been shown that IPC protects the liver more than R-IPC, this reduction in inflammatory activation may be important. In addition, this study shows that nitrite and nitrate are consumed in the liver during ischemia, unlike the levels in peripheral blood.
Publish Date	2014-07-26 13:36
Citation	Björnsson B, Winbladh A, Bojmar L, Sundqvist T, Gullstrand P, Sandström P. Conventional, but not remote ischemic preconditioning, reduces iNOS transcription in liver ischemia/reperfusion. World J Gastroenterol 2014; 20(28): 9506-9512
URL	http://www.wjgnet.com/1007-9327/full/v20/i28/9506.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i28.9506

Full Article (PDF)	WJG-20-9506.pdf
Full Article (Word)	WJG-20-9506.doc
Manuscript File	9443-Review.doc
Answering Reviewers	9443-Answering reviewers.pdf
Copyright License Agreement	9443-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	9443-Language certificate.pdf
Peer-review Report	9443-Peer review(s).pdf
Scientific Misconduct Check	9443-CrossCheck.jpg
Scientific Editor Work List	9443-Scientific editor work list.pdf