Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	94432
Country	India

Received	2024-03-18 14:29
Peer-Review Started	2024-03-18 14:29
To Make the First Decision
Return for Revision	2024-05-09 07:24
Revised	2024-06-04 18:33
Second Decision	2024-06-25 02:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-06-25 10:15
Articles in Press	2024-06-25 10:15
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-07-01 02:40
Typeset the Manuscript	2024-08-01 07:08
Publish the Manuscript Online	2024-08-30 07:27

ISSN	2219-2808 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Endocrinology & Metabolism
Manuscript Type	Observational Study
Article Title	Evaluation of thyroid profile among children aged 1-15 years with nephrotic syndrome: An observation study
Manuscript Source	Invited Manuscript
All Author List	Priyanka Kumari, Amit Agrawal and Jyotsna Shrivastava
ORCID	Author(s) ORCID Number Amit Agrawal http://orcid.org/0000-0001-6316-6700 Jyotsna Shrivastava http://orcid.org/0000-0002-5322-4791
Funding Agency and Grant Number
Corresponding Author	Amit Agrawal, MD, Associate Professor, Department of Pediatrics, Gandhi Medical College, Hamidia Hospital Campus, 49-B, Indrapuri, B-Sector, Bhopal 462022, India. agrawaldramit@yahoo.co.in
Key Words	Nephrotic syndrome; Hypothyroidism; Proteinuria; Children; Steroid - sensitive nephrotic syndrome; Steroid - resistant nephrotic syndrome
Core Tip	In nephrotic syndrome, proteinuria leads to loss of several proteins which may lead to hypothyroidism. This cross-sectional study was conducted to assess the thyroid function in children with nephrotic syndrome aged 1-15 years. Of the 70 patients, 39 (55.7%) showed abnormal thyroid profiles; 19 (27.1%) had overt hypothyroidism, and 20 (28.6%) had subclinical hypothyroidism. Overt hypothyroidism was seen in 16.1% of newly diagnosed, 40% of second relapses, and 2.7% of frequently relapsed cases (P < 0.001). An abnormal thyroid profile was commonly observed in children with nephrotic syndrome overt hypothyroidism being more common in frequently relapsing cases.
Publish Date	2024-08-30 07:27
Citation	<p>Kumari P, Agrawal A, Shrivastava J. Evaluation of thyroid profile among children aged 1-15 years with nephrotic syndrome: An observation study. <i>World J Clin Pediatr</i> 2024; 13(3): 94432</p>
URL	https://www.wjgnet.com/2219-2808/full/v13/i3/94432.htm
DOI	https://dx.doi.org/10.5409/wjcp.v13.i3.94432

Full Article (PDF)	WJCP-13-94432-with-cover.pdf
STROBE Statement	94432-STROBE-statement.pdf
Manuscript File	94432-Review-Filipodia.docx
Answering Reviewers	94432-answering-reviewers.pdf
Audio Core Tip	94432-audio.mp4
Biostatistics Review Certificate	94432-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	94432-conflict-of-interest-statement.pdf
Copyright License Agreement	94432-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s)	94432-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	94432-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	94432-non-native-speakers.pdf
Peer-review Report	94432-peer-reviews.pdf
Scientific Misconduct Check	94432-scientific-misconduct-check.png
Scientific Editor Work List	94432-scientific-editor-work-list.pdf
CrossCheck Report	94432-crosscheck-report.pdf
CrossCheck Report	94432-crosscheck-report.png