Publication Name	World Journal of Gastroenterology
Manuscript ID	9449
Country	Japan

Received	2014-02-13 08:13
Peer-Review Started	2014-02-13 08:31
To Make the First Decision	2014-03-13 19:02
Return for Revision	2014-03-23 16:02
Revised
Second Decision	2014-07-22 16:50
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-07-22 17:07
Articles in Press	2014-07-22 18:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-11-13 10:08
Publish the Manuscript Online	2014-12-02 10:46

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Hepatic clearance measured with 99mTc-GSA single-photon emission computed tomography to estimate liver fibrosis
Manuscript Source	Unsolicited Manuscript
All Author List	Masahiko Taniguchi, Atsutaka Okizaki, Kenji Watanabe, Koji Imai, Koichiro Uchida, Takahiro Einama, Noriyuki Shuke, Naoyuki Miyokawa and Hiroyuki Furukawa
Funding Agency and Grant Number
Corresponding Author	Masahiko Taniguchi, MD, Division of Gastroenterologic and General Surgery, Department of Surgery, Asahikawa Medical College, 2-1, Midorigaoka-Higashi, Asahikawa 078-8510, Japan. m-tani@asahikawa-med.ac.jp
Key Words	Fibrosis; Technetium-99m-diethylenetriaminepenta-acetic acid-galactosyl human serum albumin; Single-photon emission computed tomography; Hepatic clearance; Liver resection
Core Tip	This retrospective study evaluated the clinical utility of hepatic clearance measured with technetium-99m-diethylenetriaminepenta-acetic acid-galactosyl human serum albumin (99mTc-GSA) single-photon emission computed tomography for estimating the degree of liver fibrosis. We demonstrated that 99mTc-GSA hepatic clearance showed strong correlations with the degree of liver fibrosis and conventional liver function tests. It is a reliable index for assessing severe liver fibrosis. We believe that this quantitative index can yield a more accurate estimation of liver fibrosis compared with currently used measures before hepatectomy for hepatobiliary surgeons.
Publish Date	2014-12-02 10:46
Citation	Taniguchi M, Okizaki A, Watanabe K, Imai K, Uchida K, Einama T, Shuke N, Miyokawa N, Furukawa H. Hepatic clearance measured with 99mTc-GSA single-photon emission computed tomography to estimate liver fibrosis. World J Gastroenterol 2014; 20(44): 16714-16720
URL	http://www.wjgnet.com/1007-9327/full/v20/i44/16714.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i44. 16714

Manuscript File	9449-Review.docx
Answering Reviewers	9449-Answering reviewers.pdf
Copyright License Agreement	9449-Copyright assignment.pdf
Peer-review Report	9449-Peer review(s).pdf
Scientific Misconduct Check	9449-CrossCheck.jpg
Scientific Editor Work List	9449-Scientific editor work list.pdf