| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Clinical Neurology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Effects of glycemic indicators on early neurological outcomes in patients with acute ischemic stroke treated with intravenous thrombolysis
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zuo-Wei Duan, Zhi-Ning Li, Yu-Jia Zhai, Teng-Fei Liu, Cui-Cui Zhang, Ting Hu, Xiu-E Wei, Liang-Qun Rong and Hai-Yan Liu |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Foundation of Jiangsu Provincial Commission of Health and Family Planning |
No. QNRC2016353 |
| Commission of Health and Family Planning Xuzhou |
No. KC22206 |
|
| Corresponding Author |
Hai-Yan Liu, PhD, Department of Neurology, The Second Affiliated Hospital of Xuzhou Medical University, No. 32 Meijian Road, Xuzhou 221006, Jiangsu Province, China. sjnklhy0722@163.com |
| Key Words |
Acute ischemic stroke; Early neurological improvement; Early neurological deterioration; Stress hyperglycemia; Stress hyperglycemia ratio; Intravenous thrombolysis |
| Core Tip |
The benefit of intravenous thrombolysis (IVT) is thought to be due to arterial recanalization and brain tissue reperfusion, which improves neurological outcomes of acute ischemic stroke (AIS) patients treated with IVT. However, individual differences in the early neurological outcomes after IVT therapy are significant. Stress hyperglycemia ratio (SHR), a novel index introduced by Roberts et al, defined as admission glucose divided by estimated average glucose concentration derived from glycosylated hemoglobin, was reported to be better glycemic indicators on clinical outcomes of AIS than other absolute hyperglycemia. However, there is still no consensus about the influence of stress hyperglycemia on the effects of early neurological outcomes in AIS patients treated with IVT. The study was to identify predictors for early neurological improvement (ENI) and early neurological deterioration (END) and demonstrated that admission hyperglycemia, fasting blood glucose, and stress hyperglycemia ratio in stroke patients treated with IVT were associated with the presence of END rather ENI during the first 24 hours after admission. |
| Publish Date |
2025-01-21 09:26 |
| Citation |
<p>Duan ZW, Li ZN, Zhai YJ, Liu TF, Zhang CC, Hu T, Wei XE, Rong LQ, Liu HY. Effects of glycemic indicators on early neurological outcomes in patients with acute ischemic stroke treated with intravenous thrombolysis. <i>World J Diabetes</i> 2025; 16(3): 94491</p> |
| URL |
https://www.wjgnet.com/1948-9358/full/v16/i3/94491.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v16.i3.94491 |
