| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Lymphoepithelioma-like esophageal carcinoma with macroscopic reduction
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Masaya Uesato, Tuguaki Kono, Tooru Shiratori, Yasunori Akutsu, Isamu Hoshino, Kentarou Murakami, Daisuke Horibe, Tetsurou Maruyama, Yoshihide Semba, Ryuma Urahama, Yukiko Ogura, Takashi Oide, Toru Tanizawa and Hisahiro Matsubara |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Masaya Uesato, MD, Department of Frontier Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba 260-8670, Japan. uesato@faculty.chiba-u.jp |
| Key Words |
Esophageal cancer; Lymphoepithelioma-like carcinoma; Lymphoid stroma; Tumor-infiltrating lymphocyte; Cytotoxic T lymphocyte; Reduction |
| Core Tip |
The first case of esophageal lymphoepithelioma-like carcinoma showing macroscopic reduction is reported. In only 2 mo, the appearance of the esophageal tumor changed from a protruding lesion to a flat scar-like entity. After esophagectomy, one lymph node was diagnosed with metastasis. Prominent infiltration of T lymphoid cells that stained positive for CD8 was observed around the carcinoma cells. Strong expression of human leukocyte antigen-DR was evident in the cell membrane. The immune responses against the main tumor and the denatured carcinoma cells in the metastatic lymph node developed at the same time. Therefore, systemic immune responses against the carcinoma might have been occurring. |
| Publish Date |
2014-08-14 16:58 |
| Citation |
Uesato M, Kono T, Shiratori T, Akutsu Y, Hoshino I, Murakami K, Horibe D, Maruyama T, Semba Y, Urahama R, Ogura Y, Oide T, Tanizawa T, Matsubara H. Lymphoepithelioma-like esophageal carcinoma with macroscopic reduction. World J Gastrointest Endosc 2014; 6(8): 385-389 |
| URL |
http://www.wjgnet.com/1948-5190/full/v6/i8/385.htm |
| DOI |
http://dx.doi.org/10.4253/wjge.v6.i8.385 |
