ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Retrospective Study |
Article Title |
Validation of prognostic scores for predicting acute liver failure and in-hospital death in patients with dengue-induced severe hepatitis
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Tongluk Teerasarntipan, Kessarin Thanapirom, Roongruedee Chaiteerakij, Piyawat Komolmit and Sombat Treeprasertsuk |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
the Fatty Liver Unit, Foundation of the Faculty of Medicine, Chulalongkorn University |
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Corresponding Author |
Sombat Treeprasertsuk, MD, PhD, Professor, Division of Gastroenterology, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, 1873 Rama IV Road, Pathumwan, Bangkok 10330, Thailand. battan5410@gmail.com |
Key Words |
Fulminant; Clinical outcomes; Liver injury; Prognostic assessment; Predictive models; Mortality prediction |
Core Tip |
Although acute liver failure (ALF) from dengue infection is rare, its consequences are severe, often resulting in high mortality. Timely identification of at-risk individuals and prompt intervention are crucial for optimizing clinical outcomes. Parameters such as international normalized ratio, bilirubin, albumin, and creatinine were independent predictors associated with ALF and mortality. Incorporating these parameters into prognostic models, the model for end-stage liver disease score was the most reliable predictor of ALF and mortality in dengue-infected patients. Additionally, the easy albumin-bilirubin score, a simpler metric, exhibited excellent predictive performance, indicating its potential as an alternative prognostic tool in this patient population. |
Publish Date |
2024-11-13 10:10 |
Citation |
<p>Teerasarntipan T, Thanapirom K, Chaiteerakij R, Komolmit P, Treeprasertsuk S. Validation of prognostic scores for predicting acute liver failure and in-hospital death in patients with dengue-induced severe hepatitis. <i>World J Gastroenterol</i> 2024; 30(45): 4781-4790</p> |
URL |
https://www.wjgnet.com/1007-9327/full/v30/i45/4781.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v30.i45.4781 |