| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Nutrition & Dietetics |
| Manuscript Type |
Observational Study |
| Article Title |
Selenoprotein-p and insulin resistance in children and adolescents with obesity
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Amany Elbarky, Kholoud Gamal Ismail, Yousef Fouad Yousef, Rasha Mohamed Gamal Elshafiey, Radwa Mahmoud Elsharaby, Asmaa El-Kaffas and Mohammed Al-Beltagi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Mohammed Al-Beltagi, MBChB, MD, PhD, Academic Editor, Chairman, Full Professor, Research Scientist, Department of Pediatric, Faculty of Medicine, Tanta University, Al-Bahr Street, The Medical Complex, Tanta 31511, Alghrabia, Egypt. mbelrem@hotmail.com |
| Key Words |
Obesity; Childhood obesity; Selenium status; Selenoprotien P1; Insulin resistance |
| Core Tip |
This study investigates the association between serum Selenoprotein P1 (SEPP1) levels and insulin resistance in pediatric obesity. Conducted on 170 children, the study reveals significantly lower SEPP1 levels in obese children compared to healthy peers, with notable negative correlations between SEPP1 levels and adiposity indices such as body mass index, visceral adiposity index, and Homeostatic Model Assessment of Insulin Resistance. The findings suggest SEPP1's potential as a predictor for insulin resistance in pediatric obesity, highlighting its utility in metabolic health assessment. However, further research is needed to determine the temporal relationship between SEPP1 levels and insulin resistance onset in pediatric obesity, emphasizing the importance of continued investigation in this area for clinical practice. |
| Publish Date |
2024-08-30 07:27 |
| Citation |
<p>Elbarky A, Ismail KG, Yousef YF, Elshafiey RMG, Elsharaby RM, El-Kaffas A, Al-Beltagi M. Selenoprotein-p and insulin resistance in children and adolescents with obesity. <i>World J Clin Pediatr</i> 2024; 13(3): 94721</p> |
| URL |
https://www.wjgnet.com/2219-2808/full/v13/i3/94721.htm |
| DOI |
https://dx.doi.org/10.5409/wjcp.v13.i3.94721 |
