Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	94787
Country	China

Received	2024-03-25 13:48
Peer-Review Started	2024-03-25 13:48
To Make the First Decision
Return for Revision	2024-05-03 05:00
Revised	2024-05-24 03:21
Second Decision	2024-07-17 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-07-17 06:31
Articles in Press	2024-07-17 06:31
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-08-06 01:47
Publish the Manuscript Online	2024-09-18 11:53

ISSN	1948-9366 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Chemistry, Medicinal
Manuscript Type	Observational Study
Article Title	Advancing gastrointestinal stromal tumor management: The role of imagomics features in precision risk assessment
Manuscript Source	Unsolicited Manuscript
All Author List	Gui-Hai Pan, Fei Zhou, Wu-Biao Chen and Ze-Jun Pan
ORCID	Author(s) ORCID Number Gui-Hai Pan http://orcid.org/0000-0002-9553-3437 Fei Zhou http://orcid.org/0009-0005-2142-7040
Funding Agency and Grant Number
Corresponding Author	Fei Zhou, N/A, N/A, N/A, Department of Endocrinology, the Affiliated Hospital of Guangdong Medical University, No. 57 Renmin Avenue South, Xiashan District, Zhanjiang 524001, Guangdong Province, China. 2406790@qq.com
Key Words	Gastrointestinal stromal tumor; Magnetic resonance imaging; Imagomics, Risk stratification; Precision medicine; Diffusion-weighted imaging; T1-weighted imaging; Contrast enhanced T1-weighted imaging with fat saturation fat suppress
Core Tip	This study unveils the transformative potential of magnetic resonance imaging (MRI) imagomics in the preoperative risk stratification of gastrointestinal stromal tumors (GISTs), challenging traditional, pathology-based assessments. By analyzing imagomics features from MRI sequences, particularly diffusion-weighted imaging and a combined T1-weighted imaging (T1WI)/contrast enhanced T1WI with fat saturation fat suppress model, we have demonstrated unprecedented accuracy in predicting GIST risk levels. These findings not only enhance the precision of preoperative evaluations but also pave the way for more personalized treatment plans, aligning closely with the goals of precision medicine in oncology.
Publish Date	2024-09-18 11:53
Citation	<p>Pan GH, Zhou F, Chen WB, Pan ZJ. Advancing gastrointestinal stromal tumor management: The role of imagomics features in precision risk assessment. <i>World J Gastrointest Surg</i> 2024; 16(9): 2942-2952</p>
URL	https://www.wjgnet.com/1948-9366/full/v16/i9/2942.htm
DOI	https://dx.doi.org/10.4240/wjgs.v16.i9.2942

Full Article (PDF)	WJGS-16-2942-with-cover.pdf
STROBE Statement	94787-STROBE-statement.pdf
Manuscript File	94787_Auto_Edited_072901.docx
Answering Reviewers	94787-answering-reviewers.pdf
Audio Core Tip	94787-audio.mp3
Biostatistics Review Certificate	94787-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	94787-conflict-of-interest-statement.pdf
Copyright License Agreement	94787-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s)	94787-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	94787-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	94787-non-native-speakers.pdf
Supplementary Material	94787-supplementary-material.pdf
Peer-review Report	94787-peer-reviews.pdf
Scientific Misconduct Check	94787-scientific-misconduct-check.jpg
Scientific Editor Work List	94787-scientific-editor-work-list.pdf
CrossCheck Report	94787-crosscheck-report.pdf