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Articles Published Processes
10/31/2024 10:39:35 AM | Browse: 232 | Download: 848
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Received |
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2024-03-27 03:09 |
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Peer-Review Started |
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2024-03-27 03:09 |
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First Decision by Editorial Office Director |
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2024-08-13 22:27 |
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Return for Revision |
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2024-08-13 22:27 |
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Revised |
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2024-08-26 04:25 |
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Publication Fee Transferred |
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2024-10-17 23:14 |
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Second Decision by Editor |
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2024-10-14 02:38 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2024-10-14 07:08 |
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Articles in Press |
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2024-10-14 07:08 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-10-23 08:32 |
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Publish the Manuscript Online |
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2024-10-31 10:39 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Basic Study |
| Article Title |
Transfection of 12/15-lipoxygenase effectively alleviates inflammatory responses during experimental acute pancreatitis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hong-Wei Sun, Yong-Yu Bai, Zhen-Liu Qin, Ri-Zhao Li, Tinotenda Blessing Madzikatire, Percy David Papa Akuetteh, Qiang Li, Hong-Ru Kong and Yue-Peng Jin |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Health Commission Research Fund |
WKJ-ZJ-2342 |
| National Natural Science Foundation of China |
81900583 |
| Science and Technology Plan Project of Wenzhou |
Y20180103 |
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| Corresponding Author |
Yue-Peng Jin, PhD, Associate Chief Physician, National Key Clinical Specialty (General Surgery), The First Affiliated Hospital Of Wenzhou Medical University, Nanbaixiang Street, Wenzhou 325000, Zhejiang Province, China. quiet1981@163.com |
| Key Words |
Acute pancreatitis; Cerulein; 12/15-lipoxygenase; Apoptosis; Autophagy |
| Core Tip |
Our in vivo data demonstrated for the first time that arachidonate 15-lipoxygenase (Alox15) transfection attenuated cerulein-induced acute pancreatitis (AP) in a murine model, highlighting its regulatory role in inflammation, apoptosis, and autophagy. These findings suggested that Alox15 may serve as a potential therapeutic target for the treatment of AP by modulating the key cellular processes involved in the pathology of this disease. |
| Publish Date |
2024-10-31 10:39 |
| Citation |
Sun HW, Bai YY, Qin ZL, Li RZ, Madzikatire TB, Akuetteh PDP, Li Q, Kong HR, Jin YP. Transfection of 12/15-lipoxygenase effectively alleviates inflammatory responses during experimental acute pancreatitis. World J Gastroenterol 2024; 30(42): 4544-4556 |
| URL |
https://www.wjgnet.com/1007-9327/full/v30/i42/4544.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v30.i42.4544 |
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