Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	94867
Country	Italy

Received	2024-03-26 19:12
Peer-Review Started	2024-03-26 19:12
To Make the First Decision
Return for Revision	2024-06-04 03:50
Revised	2024-06-06 15:00
Second Decision	2024-07-12 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-07-15 02:31
Articles in Press	2024-07-15 02:31
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-08-01 08:46
Publish the Manuscript Online	2024-10-25 10:27

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Pathology
Manuscript Type	Editorial
Article Title	Practical hints for the diagnosis of mixed neuroendocrine-non-neuroendocrine neoplasms of the digestive system
Manuscript Source	Invited Manuscript
All Author List	Paola Mattiolo
ORCID	Author(s) ORCID Number Paola Mattiolo http://orcid.org/0000-0002-5601-0879
Funding Agency and Grant Number
Corresponding Author	Paola Mattiolo, MD, Research Fellow, Department of Diagnostics and Public Health, Section of Pathology, University of Verona, University and Hospital Trust of Verona, Piazzale L.A. Scuro 10, Verona 37134, Italy. paola.mattiolo@univr.it
Key Words	Mixed neuroendocrine-non-neuroendocrine neoplasm; Digestive system; Neuroendocrine neoplasm; Immunohistochemistry
Core Tip	Mixed neuroendocrine-non-neuroendocrine neoplasms are a heterogeneous group of neoplastic diseases that share histological and immunohistochemical features. The most important factor is the uncertain presence of a neuroendocrine component. The presence of entrapped neuroendocrine cells, differential diagnosis of amphicrine neoplasms, and neuroendocrine expression in non-neuroendocrine carcinoma can lead to misdiagnosis. Current guidelines require the fulfillment of volumetric criteria, but the prognostic relevance of the current cutoff remains to be proven.
Publish Date	2024-10-25 10:27
Citation	<p>Mattiolo P. Practical hints for the diagnosis of mixed neuroendocrine-non-neuroendocrine neoplasms of the digestive system. <i>World J Gastrointest Oncol</i> 2024; 16(11): 4326-4332</p>
URL	https://www.wjgnet.com/1948-5204/full/v16/i11/4326.htm
DOI	https://dx.doi.org/10.4251/wjgo.v16.i11.4326

Full Article (PDF)	WJGO-16-4326-with-cover.pdf
Manuscript File	94867_Auto_Edited_072516.docx
Answering Reviewers	94867-answering-reviewers.pdf
Audio Core Tip	94867-audio.m4a
Conflict-of-Interest Disclosure Form	94867-conflict-of-interest-statement.pdf
Copyright License Agreement	94867-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	94867-non-native-speakers.pdf
Peer-review Report	94867-peer-reviews.pdf
Scientific Misconduct Check	94867-scientific-misconduct-check.jpg
Scientific Editor Work List	94867-scientific-editor-work-list.pdf
CrossCheck Report	94867-crosscheck-report.pdf