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Articles Published Processes
8/16/2024 8:03:14 AM | Browse: 80 | Download: 216
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Received |
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2024-03-28 02:20 |
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Peer-Review Started |
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2024-03-28 02:20 |
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To Make the First Decision |
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Return for Revision |
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2024-07-03 06:00 |
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Revised |
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2024-07-15 00:31 |
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Second Decision |
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2024-07-23 02:44 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-07-23 06:39 |
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Articles in Press |
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2024-07-23 06:39 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-07-25 02:54 |
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Publish the Manuscript Online |
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2024-08-16 08:03 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: Https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Editorial |
| Article Title |
Implications of genetic testing and informed consent before and after genetic testing in individuals with cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Priyanka Kumar, David J Benjamin, Sourat Darabi, Goetz Kloecker and Arash Rezazadeh Kalebasty |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
David J Benjamin, MD, Doctor, Doctor, Department of Medical Oncology, Hoag Family Cancer Institute, 1 Hoag Drive, Building 41, Newport Beach, CA 92663, United States. david.benjamin@hoag.org |
| Key Words |
Genetic testing; Informed consent; Genetic counseling; Next generation sequencing; Mainstreaming; Layered consent |
| Core Tip |
Mainstreaming has allowed for improved and readily available access to next generation sequencing testing in some regions of the world by allowing oncologists to order genetic testing. Pitfalls encountered with mainstreaming include adequate patient counseling on unanticipated genetic results as well as follow-up of variants of unknown significance (VUS) which have implications for tested individuals and family members. Genetic registries following VUS may provide a formal avenue for patients to receive adequate follow-up and counseling if VUS are later identified as malignant. A “layered consent model” as well as system of categorizing genes of interest may help in preserving patient autonomy and upholding the medical ethical tenets of justice and non-maleficence. |
| Publish Date |
2024-08-16 08:03 |
| Citation |
<p>Kumar P, Benjamin DJ, Darabi S, Kloecker G, Rezazadeh Kalebasty A. Implications of genetic testing and informed consent before and after genetic testing in individuals with cancer. <i>World J Clin Oncol</i> 2024; 15(8): 975-981</p> |
| URL |
https://www.wjgnet.com/2218-4333/full/v15/i8/975.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v15.i8.975 |
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