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Articles Published Processes
7/8/2024 7:49:58 AM | Browse: 113 | Download: 264
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Received |
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2024-04-03 14:52 |
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Peer-Review Started |
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2024-04-03 14:52 |
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To Make the First Decision |
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Return for Revision |
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2024-04-30 09:08 |
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Revised |
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2024-05-13 02:26 |
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Second Decision |
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2024-05-22 13:00 |
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Accepted by Journal Editor-in-Chief |
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2024-05-28 20:20 |
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Accepted by Executive Editor-in-Chief |
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2024-05-29 06:14 |
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Articles in Press |
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2024-05-29 06:14 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2024-06-09 01:51 |
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Typeset the Manuscript |
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2024-06-21 11:27 |
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Publish the Manuscript Online |
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2024-07-08 07:49 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Clinical and Translational Research |
| Article Title |
Network pharmacology and molecular dynamics study of the effect of the Astragalus-Coptis drug pair on diabetic kidney disease
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Mo-Yan Zhang and Shu-Qin Zheng |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Shu-Qin Zheng, MSc, Associate Professor, Department of Endocrinology, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, No. 33 Beiling Street, Huanggu District, Shenyang 110032, Liaoning Province, China. qxjzsq@sina.com |
| Key Words |
Astragalus membranaceus; Coptis chinensis Franch; Diabetic kidney disease; Network pharmacology; Molecular docking; Molecular dynamics simulation |
| Core Tip |
Network pharmacology, molecular docking, and molecular dynamics simulation studies have demonstrated that diabetic kidney disease (DKD) treatment with the Astragalus-Coptis drug pair involves a diverse range of active ingredients, targets, and pathways. Additionally, quercetin has been found to exhibit strong affinity and binding stability with AKT serine/threonine kinase 1 and tumor necrosis factor, highlighting its potential therapeutic role in DKD. The findings of this study establish a robust theoretical basis for applying the Astragalus-Coptis drug pair in DKD treatment, and these results may provide a guiding framework for further experiments. |
| Publish Date |
2024-07-08 07:49 |
| Citation |
<p>Zhang MY, Zheng SQ. Network pharmacology and molecular dynamics study of the effect of the Astragalus-Coptis drug pair on diabetic kidney disease. <i>World J Diabetes</i> 2024; 15(7): 1562-1588</p> |
| URL |
https://www.wjgnet.com/1948-9358/full/v15/i7/1562.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v15.i7.1562 |
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