Publication Name	World Journal of Clinical Cases
Manuscript ID	95067
Country	China

Received	2024-04-04 10:13
Peer-Review Started	2024-04-04 10:13
To Make the First Decision
Return for Revision	2024-05-01 02:37
Revised	2024-05-14 16:07
Second Decision	2024-06-06 02:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-06-07 09:10
Articles in Press	2024-06-07 09:10
Publication Fee Transferred	2024-06-14 11:07
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-06-26 00:34
Publish the Manuscript Online	2024-07-01 13:38

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Meta-Analysis
Article Title	Efficacy and safety of Xileisan combined with mesalazine for ulcerative colitis: A meta-analysis and trial sequential analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Xin-Yu Yang, Yun-Feng Yu, Ke-Ke Tong, Gang Hu, Rong Yu and Lian-Jun Su
ORCID	Author(s) ORCID Number Xin-Yu Yang http://orcid.org/0000-0001-6124-9166 Yun-Feng Yu http://orcid.org/0000-0002-7309-5608 Ke-Ke Tong http://orcid.org/0000-0001-6852-3914 Gang Hu http://orcid.org/0000-0002-6252-0082 Rong Yu http://orcid.org/0009-0005-0840-2797 Lian-Jun Su http://orcid.org/0009-0006-1978-9285
Funding Agency and Grant Number	Funding Agency Grant Number Discipline Construction Project of Hunan University of Chinese Medicine 22JBZ002
Corresponding Author	Lian-Jun Su, Doctor, N/A, N/A, School of Traditional Chinese Medicine, Hunan University of Chinese Medicine, No. 300, Xueshi Road, Hanpu Science and Education Park, Yuelu District, Changsha 410208, Hunan Province, China. sulianjun@hnucm.edu.cn
Key Words	Xileisan; Mesalazine; Ulcerative colitis; Meta-analysis; Trial sequential analysis
Core Tip	The benefits and potential risks of Xileisan (XLS) in the treatment of ulcerative colitis (UC) remain unclear. The present study aimed to evaluate the efficacy and safety of XLS combined with mesalazine in the treatment of UC through meta-analysis and trial sequential analysis. The meta-analysis showed that XLS alleviated the clinical symptoms, intestinal mucosal injury, and inflammatory response in patients with UC, while demonstrating good safety. XLS, therefore, represents a safe and effective treatment strategy for UC.
Publish Date	2024-07-01 13:38
Citation	<p>Yang XY, Yu YF, Tong KK, Hu G, Yu R, Su LJ. Efficacy and safety of Xileisan combined with mesalazine for ulcerative colitis: A meta-analysis and trial sequential analysis. <i>World J Clin Cases</i> 2024; 12(21): 4703-4716</p>
URL	https://www.wjgnet.com/2307-8960/full/v12/i21/4703.htm
DOI	https://dx.doi.org/10.12998/wjcc.v12.i21.4703

Full Article (PDF)	WJCC-12-4703-with-cover.pdf
PRISMA 2009 Checklist	95067-PRISMA-2009-Checklist.pdf
Manuscript File	95067_Auto_Edited-JLW.docx
Answering Reviewers	95067-answering-reviewers.pdf
Audio Core Tip	95067-audio.mp3
Biostatistics Review Certificate	95067-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	95067-conflict-of-interest-statement.pdf
Copyright License Agreement	95067-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	95067-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	95067-non-native-speakers.pdf
Peer-review Report	95067-peer-reviews.pdf
Scientific Misconduct Check	95067-scientific-misconduct-check.png
Scientific Editor Work List	95067-scientific-editor-work-list.pdf
CrossCheck Report	95067-crosscheck-report.pdf