Publication Name	World Journal of Clinical Cases
Manuscript ID	95086
Country	China

Received	2024-04-30 10:58
Peer-Review Started	2024-04-30 10:58
To Make the First Decision
Return for Revision	2024-05-20 16:24
Revised	2024-05-29 09:10
Second Decision	2024-06-14 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-06-14 07:48
Articles in Press	2024-06-14 07:48
Publication Fee Transferred	2024-06-18 08:46
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-06-26 12:55
Publish the Manuscript Online	2024-07-02 08:41

ISSN	2307-8960 (online)
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Category	Obstetrics & Gynecology
Manuscript Type	Retrospective Study
Article Title	Clinical efficacy of gamma-oryzanol combined with Femoston for perimenopausal syndrome
Manuscript Source	Unsolicited Manuscript
All Author List	Yang-Yang Kuang, Min-Qi Xiong and Jin-Xia Cai
ORCID	Author(s) ORCID Number Yang-Yang Kuang http://orcid.org/0009-0002-2749-8120
Funding Agency and Grant Number
Corresponding Author	Yang-Yang Kuang, MM, Doctor, Doctor, Women's Health Management Center, Jiujiang Maternal and Child Health Hospital, No. 61 Gantang South Road, Xunyang District, Jiujiang 332000, Jiangxi Province, China. 13576207600@163.com
Key Words	γ-oryzanol; Femoston; Perimenopausal syndrome; Clinical effectiveness; Adverse reactions
Core Tip	Perimenopausal syndrome (PMS) is a chronic condition associated with estrogen deficiency. Hormone replacement therapy is the conventional treatment for PMS; however, because of possible adverse events such as stroke, breast cancer, endometrial cancer, glucose intolerance, and thromboembolic disease, its treatment alternatives must be continuously explored and optimized. Compared with Femoston monotherapy, proposed combination therapy of γ-oryzanol and Femoston has certain clinical advantages, including significantly better clinical efficacy, for treating patients with PMS. This treatment can prevent adverse reactions, actively regulate sex hormone levels, increase patient bone mineral density, and actively help improve sleep quality.
Publish Date	2024-07-02 08:41
Citation	<p>Kuang YY, Xiong MQ, Cai JX. Clinical efficacy of gamma-oryzanol combined with Femoston for perimenopausal syndrome. <i>World J Clin Cases</i> 2024; 12(22): 4992-4998</p>
URL	https://www.wjgnet.com/2307-8960/full/v12/i22/4992.htm
DOI	https://dx.doi.org/10.12998/wjcc.v12.i22.4992

Full Article (PDF)	WJCC-12-4992-with-cover.pdf
Manuscript File	95086_Auto_Edited-LJH-JLW.docx
Answering Reviewers	95086-answering-reviewers.pdf
Audio Core Tip	95086-audio.mp3
Biostatistics Review Certificate	95086-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	95086-conflict-of-interest-statement.pdf
Copyright License Agreement	95086-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s)	95086-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	95086-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	95086-non-native-speakers.pdf
Peer-review Report	95086-peer-reviews.pdf
Scientific Misconduct Check	95086-scientific-misconduct-check.png
Scientific Editor Work List	95086-scientific-editor-work-list.pdf
CrossCheck Report	95086-crosscheck-report.pdf
CrossCheck Report	95086-crosscheck-report.png