Publication Name	World Journal of Diabetes
Manuscript ID	95123
Country	China

Received	2024-04-02 06:51
Peer-Review Started	2024-04-02 06:51
To Make the First Decision
Return for Revision	2024-07-28 22:41
Revised	2024-08-17 17:14
Second Decision	2024-09-14 07:50
Accepted by Journal Editor-in-Chief	2024-09-20 16:00
Accepted by Executive Editor-in-Chief	2024-09-23 08:15
Articles in Press	2024-09-23 08:15
Publication Fee Transferred	2024-09-24 07:23
Edit the Manuscript by Language Editor	2024-09-30 15:15
Typeset the Manuscript	2024-10-14 00:11
Publish the Manuscript Online	2024-10-16 10:39

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Pharmacology & Pharmacy
Manuscript Type	Basic Study
Article Title	Tiliroside protects against diabetic nephropathy in streptozotocin-induced diabetes rats by attenuating oxidative stress and inflammation
Manuscript Source	Unsolicited Manuscript
All Author List	Yan Shang, Cai-Yun Yan, Hui Li, Na Liu and Hui-Feng Zhang
ORCID	Author(s) ORCID Number Hui-Feng Zhang http://orcid.org/0009-0004-1197-3307
Funding Agency and Grant Number
Corresponding Author	Hui-Feng Zhang, MM, Doctor, Doctor, Department of Nephrology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, No. 99 Longcheng Street, Xiaodian District, Taiyuan 030032, Shanxi Province, China. zhanghuifeng1977@163.com
Key Words	Tiliroside; Diabetic nephropathy; Antioxidant; Diabetes mellitus; Oxidative stress; Inflammation
Core Tip	Tiliroside (Til) demonstrates potent protective effects against diabetic nephropathy (DN) in Sprague Dawley rats, alongside glibenclamide. Through attenuating oxidative stress, inflammation, and fibrosis, Til treatment significantly improves renal function and reduces biochemical markers associated with DN. Molecular docking analysis reveals its potential inhibition of key markers linked to the disease. These findings underscore Til's promising role as a therapeutic agent for DN, suggesting avenues for future drug development.
Publish Date	2024-10-16 10:39
Citation	<p>Shang Y, Yan CY, Li H, Liu N, Zhang HF. Tiliroside protects against diabetic nephropathy in streptozotocin-induced diabetes rats by attenuating oxidative stress and inflammation. <i>World J Diabetes</i> 2024; 15(11): 2220-2236</p>
URL	https://www.wjgnet.com/1948-9358/full/v15/i11/2220.htm
DOI	https://dx.doi.org/10.4239/wjd.v15.i11.2220

Full Article (PDF)	WJD-15-2220-with-cover.pdf
The ARRIVE Guidelines	95123-The-ARRIVE-Guidelines.pdf
Manuscript File	95123_Auto_Edited_032931.docx
Answering Reviewers	95123-answering-reviewers.pdf
Audio Core Tip	95123-audio.MP3
Biostatistics Review Certificate	95123-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	95123-conflict-of-interest-statement.pdf
Copyright License Agreement	95123-copyright-assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	95123-institutional-animal-care-and-use-committee-statement.pdf
Institutional Review Board Approval Form or Document	95123-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	95123-non-native-speakers.pdf
Peer-review Report	95123-peer-reviews.pdf
Journal Editor-in-Chief Review Report	95123-journal-editor-in-chief.pdf
Scientific Misconduct Check	95123-scientific-misconduct-check.png
Scientific Editor Work List	95123-scientific-editor-work-list.pdf
CrossCheck Report	95123-crosscheck-report.pdf