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Articles Published Processes
7/26/2024 6:56:10 AM | Browse: 180 | Download: 872
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Received |
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2024-04-04 04:56 |
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Peer-Review Started |
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2024-04-04 04:56 |
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First Decision by Editorial Office Director |
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2024-05-11 08:04 |
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Return for Revision |
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2024-05-11 08:04 |
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Revised |
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2024-05-28 07:58 |
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Publication Fee Transferred |
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2024-07-09 02:50 |
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Second Decision by Editor |
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2024-06-17 06:37 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2024-06-26 07:38 |
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Articles in Press |
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2024-06-26 07:38 |
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Edit the Manuscript by Language Editor |
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2024-07-13 16:21 |
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Typeset the Manuscript |
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2024-07-18 09:49 |
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Publish the Manuscript Online |
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2024-07-26 06:56 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Case Control Study |
| Article Title |
Autoantibodies against beta cell to predict early insulin requirements in pediatric patients with clinically diagnosed type 2 diabetes
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jorge M Molina, Patricia G Medina, Rita A Gomez, Julia R Herrera, Nancy L Martínez, Brenda Hernández and Yesenia García |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Mexican Federal Funds HIM |
2018/068 SSA152 |
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| Corresponding Author |
Jorge M Molina, PhD, Doctor, Doctor, Department of Endocrinology, Children’s Hospital Federico Gomez, Dr. Márquez 162, Colonia Doctores, Cuauhtemoc, Mexico 06720, Mexico. dereck79@live.com.mx |
| Key Words |
Insulin requirements; Beta cell; Autoimmunity; Adolescents; Obesity; Diabetes |
| Core Tip |
We found that patients with type 2 diabetes in pediatric age show a more aggressive phenotype of the disease, with a significant depletion of beta cell function, and where antibodies against pancreatic beta cells were associated with lower levels of insulin and C-peptide conferring a higher risk of early dependence on exogenous insulin. Therefore, in a pediatric patient with type 2 diabetes mellitus phenotype, the determination of pancreatic antibodies can be a clinical tool to predict early insulin requirements, leading to closer control of the disease to avoid chronic complications. |
| Publish Date |
2024-07-26 06:56 |
| Citation |
Molina JM, Medina PG, Gomez RA, Herrera JR, Martínez NL, Hernández B, García Y. Autoantibodies against beta cell to predict early insulin requirements in pediatric patients with clinically diagnosed type 2 diabetes. World J Diabetes 2024; 15(8): 1717-1725 |
| URL |
https://www.wjgnet.com/1948-9358/full/v15/i8/1717.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v15.i8.1717 |
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