Publication Name	World Journal of Diabetes
Manuscript ID	95252
Country	Egypt

Received	2024-04-06 07:10
Peer-Review Started	2024-04-06 07:10
To Make the First Decision
Return for Revision	2024-06-07 03:57
Revised	2024-06-30 16:11
Second Decision	2024-07-09 11:08
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-07-17 08:06
Articles in Press	2024-07-17 08:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-07-19 03:57
Publish the Manuscript Online	2024-07-26 06:56

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Biochemistry & Molecular Biology
Manuscript Type	Basic Study
Article Title	Mitigating diabetes-related complications: Empowering metformin with cholecalciferol and taurine supplementation in type 2 diabetic rats
Manuscript Source	Invited Manuscript
All Author List	Mai S Attia, Fadwa Ayman, Mohamed S Attia, Galal Yahya, Mansour H Zahra, Magdi Mohamed Ibrahim Khalil and Abdel Aziz A Diab
ORCID	Author(s) ORCID Number Fadwa Ayman http://orcid.org/0000-0001-7316-3394
Funding Agency and Grant Number
Corresponding Author	Fadwa Ayman, BSc, Master's Student, Research Assistant, Teaching Assistant, Department of Zoology, Faculty of Science, Faculty of Science Primary Building, Shaibet an Nakareyah, Zagazig 44519, Egypt. fadwaayman@zu.edu.eg
Key Words	Diabetes complications; Metformin; Cholecalciferol; Taurine; Glycated hemoglobin%; Antioxidant
Core Tip	Supplementation of cholecalciferol and taurine in conjunction with metformin shows promise in enhancing the management of type 2 diabetes by addressing hyperglycemia and minimizing the risk of associated complications. This combination therapy demonstrates antioxidative, anti-inflammatory, and anti-apoptotic properties, leading to improvements in glucose and insulin levels, Homeostasis Model Assessment of Insulin Resistance, glycated hemoglobin%, lipid profiles, liver function markers, and oxidative stress markers in diabetic rats. The proposed regimen also promotes recovery of pancreatic islet mass, highlighting its potential to mitigate diabetic complications.
Publish Date	2024-07-26 06:56
Citation	<p>Attia MS, Ayman F, Attia MS, Yahya G, Zahra MH, Khalil MMI, Diab AAA. Mitigating diabetes-related complications: Empowering metformin with cholecalciferol and taurine supplementation in type 2 diabetic rats. <i>World J Diabetes</i> 2024; 15(8): 1778-1792</p>
URL	https://www.wjgnet.com/1948-9358/full/v15/i8/1778.htm
DOI	https://dx.doi.org/10.4239/wjd.v15.i8.1778

Full Article (PDF)	WJD-15-1778-with-cover.pdf
The ARRIVE Guidelines	95252-The-ARRIVE-Guidelines.pdf
Manuscript File	95252_Auto_Edited_011947.docx
Answering Reviewers	95252-answering-reviewers.pdf
Audio Core Tip	95252-audio.mp3
Biostatistics Review Certificate	95252-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	95252-conflict-of-interest-statement.pdf
Copyright License Agreement	95252-copyright-assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	95252-institutional-animal-care-and-use-committee-statement.pdf
Non-Native Speakers of English Editing Certificate	95252-non-native-speakers.pdf
Peer-review Report	95252-peer-reviews.pdf
Journal Editor-in-Chief Review Report	95252-journal-editor-in-chief.pdf
Scientific Misconduct Check	95252-scientific-misconduct-check.png
Scientific Editor Work List	95252-scientific-editor-work-list.pdf
CrossCheck Report	95252-crosscheck-report.png
CrossCheck Report	95252-crosscheck-report.pdf