Publication Name	World Journal of Clinical Oncology
Manuscript ID	95328
Country	China

Received	2024-04-08 03:28
Peer-Review Started	2024-04-08 03:28
To Make the First Decision
Return for Revision	2024-08-03 06:11
Revised	2024-08-16 03:23
Second Decision	2024-08-21 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-08-21 06:46
Articles in Press	2024-08-21 06:46
Publication Fee Transferred	2024-08-22 02:53
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-09-07 10:53
Publish the Manuscript Online	2024-09-29 06:08

ISSN	2218-4333 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Case Report
Article Title	Hypofractionated and intensity-modulated radiotherapy combined with systemic therapy in metastatic hepatocellular carcinoma: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Qiu-Qiu Chen, Chun-Qiao Chen, Jin-Kun Liu, Ming-Yue Huang, Min Pan and Hui Huang
ORCID	Author(s) ORCID Number Chun-Qiao Chen http://orcid.org/0009-0004-6614-3933 Hui Huang http://orcid.org/0000-0002-4232-9416
Funding Agency and Grant Number	Funding Agency Grant Number Guangxi Guilin Science and Technology Fund 20220139-9-8
Corresponding Author	Hui Huang, MD, Doctor, Doctor, Department of Oncology, People’s Hospital of Guilin, No. 12 Wenming Road, Guilin 541002, Guangxi Zhuang Autonomous Region, China. huanghui25002@163.com
Key Words	Hypofractionated therapy; Intensity-modulated radiation; Hepatocellular carcinoma; Metastasis; Case report
Core Tip	We report a 41-year-old man diagnosed with metastatic hepatocellular carcinoma (HCC) (T3N1M1 stage IVB), and discuss its imaging and hypofractionated and intensity-modulated radiotherapy combined with systemic therapy. The treatment showed good efficacy. The patient survived for 18 months without disease progression and stable disease persisted for > 38 months. These findings demonstrated that targeted therapy and immunotherapy followed by hypofractionated and intensity-modulated radiotherapy is a promising treatment regimen for advanced metastatic HCC, which is safe and controllable.
Publish Date	2024-09-29 06:08
Citation	<p>Chen QQ, Chen CQ, Liu JK, Huang MY, Pan M, Huang H. Hypofractionated and intensity-modulated radiotherapy combined with systemic therapy in metastatic hepatocellular carcinoma: A case report. <i>World J Clin Oncol</i> 2024; 15(10): 1342-1350</p>
URL	https://www.wjgnet.com/2218-4333/full/v15/i10/1342.htm
DOI	https://dx.doi.org/10.5306/wjco.v15.i10.1342

Full Article (PDF)	WJCO-15-1342-with-cover.pdf
CARE Checklist–2016	95328-CARE-Checklist-2016.pdf
Manuscript File	95328_Auto_Edited_011713.docx
Answering Reviewers	95328-answering-reviewers.pdf
Audio Core Tip	95328-audio.mp3
Conflict-of-Interest Disclosure Form	95328-conflict-of-interest-statement.pdf
Copyright License Agreement	95328-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	95328-foundation-statement.pdf
Signed Consent for Treatment Form(s) or Document(s)	95328-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate	95328-non-native-speakers.pdf
Peer-review Report	95328-peer-reviews.pdf
Scientific Misconduct Check	95328-scientific-misconduct-check.png
Scientific Editor Work List	95328-scientific-editor-work-list.pdf
CrossCheck Report	95328-crosscheck-report.pdf